TY - JOUR
T1 - Feasibility of a modified cone-beam CT rotation trajectory to improve liver periphery visualization during transarterial chemoembolization1
AU - Schernthaner, Rüdiger E.
AU - Chapiro, Julius
AU - Sahu, Sonia
AU - Withagen, Paul
AU - Duran, Rafael
AU - Sohn, Jae Ho
AU - Radaelli, Alessandro
AU - Van Der Bom, Imramsjah Martin
AU - Geschwind, Jean François H.
AU - Lin, Mingde
N1 - Publisher Copyright:
© RSNA, 2015.
PY - 2015/12
Y1 - 2015/12
N2 - Purpose: To compare liver coverage and tumor detectability by using preprocedural magnetic resonance (MR) images as a reference, as well as radiation exposure of cone-beam computed tomography (CT) with different rotational trajectories. Materials and Methods: Fifteen patients (nine men and six women; mean age 6 standard deviation, 65 years 6 5) with primary or secondary liver cancer were retrospectively included in this institutional review board-approved study. A modified conebeam CT protocol was used in which the C-arm rotates from +55° to 2185° (open arc cone-beam CT) instead of 2120° to +120° (closed arc cone-beam CT). Each patient underwent two sessions of transarterial chemoembolization between February 2013 and March 2014 with closed arc and open arc cone-beam CT (during the first and second transarterial chemoembolization sessions, respectively, as part of the institutional transarterial chemoembolization protocol). For each cone-beam CT examination, liver volume and tumor detectability were assessed by using MR images as the reference. Radiation exposure was compared by means of a phantom study. For statistical analysis, paired t tests and a Wilcoxon signed rank test were performed. Results: Mean liver volume imaged was 1695 cm3 6 542 and 1857 cm3 6 571 at closed arc and open arc cone-beam CT, respectively. The coverage of open arc cone-beam CT was significantly higher compared with closed arc cone-beam CT (97% vs 86% of the MR imaging liver volume, P = .002). In eight patients (53%), tumors were partially or completely outside the closed arc cone-beam CT field of view. All tumors were within the open arc cone-beam CT field of view. The open arc cone-beam CT radiation exposure by means of weighted CT index was slightly lower compared with that of closed arc cone-beam CT (25.1%). Conclusion: Open arc cone-beam CT allowed for a significantly improved intraprocedural depiction of peripheral hepatic tumors while achieving a slight radiation exposure reduction.
AB - Purpose: To compare liver coverage and tumor detectability by using preprocedural magnetic resonance (MR) images as a reference, as well as radiation exposure of cone-beam computed tomography (CT) with different rotational trajectories. Materials and Methods: Fifteen patients (nine men and six women; mean age 6 standard deviation, 65 years 6 5) with primary or secondary liver cancer were retrospectively included in this institutional review board-approved study. A modified conebeam CT protocol was used in which the C-arm rotates from +55° to 2185° (open arc cone-beam CT) instead of 2120° to +120° (closed arc cone-beam CT). Each patient underwent two sessions of transarterial chemoembolization between February 2013 and March 2014 with closed arc and open arc cone-beam CT (during the first and second transarterial chemoembolization sessions, respectively, as part of the institutional transarterial chemoembolization protocol). For each cone-beam CT examination, liver volume and tumor detectability were assessed by using MR images as the reference. Radiation exposure was compared by means of a phantom study. For statistical analysis, paired t tests and a Wilcoxon signed rank test were performed. Results: Mean liver volume imaged was 1695 cm3 6 542 and 1857 cm3 6 571 at closed arc and open arc cone-beam CT, respectively. The coverage of open arc cone-beam CT was significantly higher compared with closed arc cone-beam CT (97% vs 86% of the MR imaging liver volume, P = .002). In eight patients (53%), tumors were partially or completely outside the closed arc cone-beam CT field of view. All tumors were within the open arc cone-beam CT field of view. The open arc cone-beam CT radiation exposure by means of weighted CT index was slightly lower compared with that of closed arc cone-beam CT (25.1%). Conclusion: Open arc cone-beam CT allowed for a significantly improved intraprocedural depiction of peripheral hepatic tumors while achieving a slight radiation exposure reduction.
UR - http://www.scopus.com/inward/record.url?scp=84948799003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948799003&partnerID=8YFLogxK
U2 - 10.1148/radiol.2015142821
DO - 10.1148/radiol.2015142821
M3 - Article
C2 - 26000642
AN - SCOPUS:84948799003
VL - 277
SP - 833
EP - 841
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 3
ER -