Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique

Philippe Cavailler, Marcelino Lucas, Valerie Perroud, Margaret McChesney, Sonia Ampuero, Philippe J. Guérin, Dominique Legros, Thomas Nierle, Claude Mahoudeau, Bruno Lab, Pierre Kahozi, Jacqueline L. Deen, Lorenz von Seidlein, Xuan Yi Wang, Mahesh Puri, Mohammad Ali, John D. Clemens, Francisco Songane, Alberto Baptista, Fauzia IsmaelAvertino Barreto, Claire Lise Chaignat

Research output: Contribution to journalArticlepeer-review

Abstract

We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood of Beira, Mozambique. The campaign was conducted from December 2003 to January 2004. Overall 98,152 doses were administered, and vaccine coverage of the target population was 58.6% and 53.6% for the first and second rounds, respectively. The direct cost of the campaign, which excludes the price of the vaccine, amounted to slightly over $90,000, resulting in the cost per fully vaccinated person of $2.09, which is relatively high. However, in endemic settings where outbreaks are likely to occur, integrating cholera vaccination into the routine activities of the public health system could reduce such costs.

Original languageEnglish (US)
Pages (from-to)4890-4895
Number of pages6
JournalVaccine
Volume24
Issue number22
DOIs
StatePublished - May 29 2006
Externally publishedYes

Keywords

  • Cholera
  • Cost
  • Mass-vaccination
  • Mozambique

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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