Fear of birth defects is a major barrier to soil-transmitted helminth treatment (STH) for pregnant women in the Philippines

Emily R. Insetta, Alex J. Soriano, Francis Isidore G Totañes, Bernard J C Macatangay, Vicente Y. Belizario

Research output: Contribution to journalArticle

Abstract

The World Health Organization recommends anthelminthic treatment for pregnant women after the first trimester in soil-transmitted helminth (STH) endemic regions to prevent adverse maternal-fetal consequences. Although studies have shown the high prevalence of infection in the Philippines, no research has evaluated deworming practices. We hypothesized that pregnant women are not receiving deworming treatment and we aimed to identify barriers to World Health Organization guideline implementation. We conducted key informant interviews with local Department of Health (DOH) administrators, focus group discussions with nurses, midwives, and health care workers, and knowledge, attitudes, and practices surveys with women of reproductive age to elicit perspectives about deworming during pregnancy. Key informant interviews revealed that healthcare workers were not deworming pregnant women due to inadequate drug supply, infrastructure and personnel as well as fear of teratogenicity. Focus group discussions showed that healthcare workers similarly had not implemented guidelines due to infrastructure challenges and concerns for fetal malformations. The majority of local women believed that STH treatment causes side effects (74.8%) as well as maternal harm (67.3%) and fetal harm (77.9%). Women who were willing to take anthelminthics while pregnant had significantly greater knowledge as demonstrated by higher Treatment Scores (mean rank 146.92 versus 103.1, z = -4.40, p<0.001) and higher Birth Defect Scores (mean rank 128.09 versus 108.65, z = -2.43, p = 0.015). This study concludes that World Health Organization guidelines are not being implemented in the Philippines. Infrastructure, specific protocols, and education for providers and patients regarding anthelminthic treatment are necessary for the successful prevention of STH morbidity and mortality among pregnant women.

Original languageEnglish (US)
Article numbere85992
JournalPLoS One
Volume9
Issue number2
DOIs
StatePublished - Feb 26 2014
Externally publishedYes

Fingerprint

deworming
Philippines
Helminths
pregnant women
fearfulness
helminths
Fear
Pregnant Women
World Health Organization
Soil
health care workers
Health
infrastructure
Soils
Defects
focus groups
soil
interviews
midwives
teratogenicity

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Insetta, E. R., Soriano, A. J., Totañes, F. I. G., Macatangay, B. J. C., & Belizario, V. Y. (2014). Fear of birth defects is a major barrier to soil-transmitted helminth treatment (STH) for pregnant women in the Philippines. PLoS One, 9(2), [e85992]. https://doi.org/10.1371/journal.pone.0085992

Fear of birth defects is a major barrier to soil-transmitted helminth treatment (STH) for pregnant women in the Philippines. / Insetta, Emily R.; Soriano, Alex J.; Totañes, Francis Isidore G; Macatangay, Bernard J C; Belizario, Vicente Y.

In: PLoS One, Vol. 9, No. 2, e85992, 26.02.2014.

Research output: Contribution to journalArticle

Insetta, Emily R. ; Soriano, Alex J. ; Totañes, Francis Isidore G ; Macatangay, Bernard J C ; Belizario, Vicente Y. / Fear of birth defects is a major barrier to soil-transmitted helminth treatment (STH) for pregnant women in the Philippines. In: PLoS One. 2014 ; Vol. 9, No. 2.
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