FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma

Vasavi Paidpally; Alin Chirindel; Stella Lam; Nishant Agrawal; Harry Quon; Rathan M. Subramaniam

doi:10.2217/iim.12.60

FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma

Vasavi Paidpally, Alin Chirindel, Stella Lam, Nishant Agrawal, Harry Quon, Rathan M. Subramaniam

School of Medicine

Research output: Contribution to journal › Review article › peer-review

70 Scopus citations

Abstract

This article discusses the value of ¹⁸F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. ¹⁸F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUV_max and SUV_peak), metabolic tumor volume and total lesion glycolysis are the common ¹⁸F-fluoro-2- deoxyglucose quantitative parameters that have been studied, along with qualitative assessments. These parameters will be evaluated with respect to their established or potential role as noninvasive biomarkers for patient risk stratification, treatment response and survival outcome.

Original language	English (US)
Pages (from-to)	633-647
Number of pages	15
Journal	Imaging in Medicine
Volume	4
Issue number	6
DOIs	https://doi.org/10.2217/iim.12.60
State	Published - Dec 2012

Keywords

FDG
PET/CT
head and neck squamous cell carcinoma
imaging biomarkers

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

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10.2217/iim.12.60

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title = "FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma",

abstract = "This article discusses the value of 18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. 18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUVmax and SUVpeak), metabolic tumor volume and total lesion glycolysis are the common 18F-fluoro-2- deoxyglucose quantitative parameters that have been studied, along with qualitative assessments. These parameters will be evaluated with respect to their established or potential role as noninvasive biomarkers for patient risk stratification, treatment response and survival outcome.",

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AU - Paidpally, Vasavi

AU - Chirindel, Alin

AU - Lam, Stella

AU - Agrawal, Nishant

AU - Quon, Harry

AU - Subramaniam, Rathan M.

PY - 2012/12

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N2 - This article discusses the value of 18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. 18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUVmax and SUVpeak), metabolic tumor volume and total lesion glycolysis are the common 18F-fluoro-2- deoxyglucose quantitative parameters that have been studied, along with qualitative assessments. These parameters will be evaluated with respect to their established or potential role as noninvasive biomarkers for patient risk stratification, treatment response and survival outcome.

AB - This article discusses the value of 18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. 18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUVmax and SUVpeak), metabolic tumor volume and total lesion glycolysis are the common 18F-fluoro-2- deoxyglucose quantitative parameters that have been studied, along with qualitative assessments. These parameters will be evaluated with respect to their established or potential role as noninvasive biomarkers for patient risk stratification, treatment response and survival outcome.

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KW - PET/CT

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KW - imaging biomarkers

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FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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