Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner

Medicine & Life Sciences

• fatostatin 100%
• SREBP cleavage-activating protein 88%
• Sterol Regulatory Element Binding Proteins 64%
• Endoplasmic Reticulum 45%
• Growth 24%
• Lipids 13%
• Vesicular Stomatitis 13%
• site 1 membrane-bound transcription factor peptidase 9%
• Glycoproteins 9%
• Viruses 7%
• Lipoma 6%
• Fatty Liver 5%
• Drug Development 5%
• Fatty Acids 4%
• Liver Diseases 4%
• Triglycerides 4%
• Transcription Factors 3%
• Proteins 3%
• Cholesterol 3%
• Homeostasis 3%
• Insulin 3%
• Cell Proliferation 3%
• Gene Expression 3%
• Membranes 3%

Chemical Compounds

• Cleavage 32%
• Block Like Crystal 32%
• Sterol 24%
• Protein 19%
• Lipid 6%
• Glycoprotein 5%
• Triglyceride 3%
• Cholesterol 2%
• Fatty Acid 2%
• Drug 1%