TY - JOUR
T1 - Fast acquisition of high-resolution 2D NMR spectroscopy in inhomogeneous magnetic fields
AU - Lin, Liangjie
AU - Wei, Zhiliang
AU - Zeng, Qing
AU - Yang, Jian
AU - Lin, Yanqin
AU - Chen, Zhong
N1 - Funding Information:
This work was partially supported by the National Natural Science Foundation of China [Grant Nos. 11105114 , 11375147 ], and the Natural Science Foundation of Fujian Province of China [Grant No. 2014J05012 ].
Publisher Copyright:
© 2016 Elsevier B.V. All rights reserved.
PY - 2016/5/16
Y1 - 2016/5/16
N2 - High-resolution nuclear magnetic resonance (NMR) spectroscopy plays an important role in chemical and biological analyses. In this study, we combine the J-coupling coherence transfer module with the echo-train acquisition technique for fast acquisition of high-resolution 2D NMR spectra in magnetic fields with unknown spatial variations. The proposed method shows satisfactory performance on a 5 mM ethyl 3-bromopropionate sample, under a 5-kHz (10 ppm at 11.7 T) B0 inhomogeneous field, as well as under varying degrees of pulse-flip-angle deviations. Moreover, a simulative ex situ NMR measurement is also conducted to show the effectiveness of the proposed pulse sequence.
AB - High-resolution nuclear magnetic resonance (NMR) spectroscopy plays an important role in chemical and biological analyses. In this study, we combine the J-coupling coherence transfer module with the echo-train acquisition technique for fast acquisition of high-resolution 2D NMR spectra in magnetic fields with unknown spatial variations. The proposed method shows satisfactory performance on a 5 mM ethyl 3-bromopropionate sample, under a 5-kHz (10 ppm at 11.7 T) B0 inhomogeneous field, as well as under varying degrees of pulse-flip-angle deviations. Moreover, a simulative ex situ NMR measurement is also conducted to show the effectiveness of the proposed pulse sequence.
KW - Echo train acquisition
KW - High-resolution
KW - Inhomogeneous fields
KW - NMR
KW - Scalar-coupling coherence transfer
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U2 - 10.1016/j.cplett.2016.04.015
DO - 10.1016/j.cplett.2016.04.015
M3 - Article
AN - SCOPUS:84964403207
SN - 0009-2614
VL - 652
SP - 62
EP - 67
JO - Chemical Physics Letters
JF - Chemical Physics Letters
ER -