Fast acquisition of high-resolution 2D NMR spectroscopy in inhomogeneous magnetic fields

Liangjie Lin, Zhiliang Wei, Qing Zeng, Jian Yang, Yanqin Lin, Zhong Chen

Research output: Contribution to journalArticlepeer-review

Abstract

High-resolution nuclear magnetic resonance (NMR) spectroscopy plays an important role in chemical and biological analyses. In this study, we combine the J-coupling coherence transfer module with the echo-train acquisition technique for fast acquisition of high-resolution 2D NMR spectra in magnetic fields with unknown spatial variations. The proposed method shows satisfactory performance on a 5 mM ethyl 3-bromopropionate sample, under a 5-kHz (10 ppm at 11.7 T) B0 inhomogeneous field, as well as under varying degrees of pulse-flip-angle deviations. Moreover, a simulative ex situ NMR measurement is also conducted to show the effectiveness of the proposed pulse sequence.

Original languageEnglish (US)
Pages (from-to)62-67
Number of pages6
JournalChemical Physics Letters
Volume652
DOIs
StatePublished - May 16 2016
Externally publishedYes

Keywords

  • Echo train acquisition
  • High-resolution
  • Inhomogeneous fields
  • NMR
  • Scalar-coupling coherence transfer

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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