Abstract
A new method to perform rapid 3D fMRI in human brain is introduced and evaluated in normal subjects, on a standard clinical scanner at 1.5 Tesla. The method combines a highly stable gradient echo technique with a spiral scan method, to detect brain activation related changes in blood oxygenation with high sensitivity. A motor activation paradigm with a duration of less than 5 min, performed on 10 subjects, consistently showed significant changes in signal intensity in the area of the motor cortex. In all subjects, these changes survived high statistical thresholds.
Original language | English (US) |
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Pages (from-to) | 620-626 |
Number of pages | 7 |
Journal | Magnetic resonance in medicine |
Volume | 36 |
Issue number | 4 |
DOIs | |
State | Published - Oct 1996 |
Externally published | Yes |
Keywords
- MRI
- fMRI
- motor cortex
- spiral scanning
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging