Farnesyltransferase inhibitor tipifarnib inhibits rheb prenylation and stabilizes bax in acute myelogenous leukemia cells

Husheng Ding, Jennifer S. Mcdonald, Seongseok Yun, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, David A. Loegering, Ann L. Oberg, Shaun M. Riska, Shengbing Huang, Frank A. Sinicrope, Alex A. Adjei, Judith E. Karp, X. Wei Meng, Scott H. Kaufmann

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Medicine & Life Sciences