Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy

J. H. Biddison; D. H. Dembo; H. Spalt; M. G. Hayes; C. W. LeDoux

doi:10.1161/01.CIR.59.6.1299

Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy

J. H. Biddison, D. H. Dembo, H. Spalt, M. G. Hayes, C. W. LeDoux

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.

Original language	English (US)
Pages (from-to)	1299-1304
Number of pages	6
Journal	Unknown Journal
Volume	59
Issue number	6
DOIs	https://doi.org/10.1161/01.CIR.59.6.1299
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1161/01.CIR.59.6.1299

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abstract = "A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.",

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AU - LeDoux, C. W.

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Y1 - 1979

N2 - A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.

AB - A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.

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Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy

Abstract

ASJC Scopus subject areas

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