Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy

J. H. Biddison, D. H. Dembo, H. Spalt, M. G. Hayes, C. W. LeDoux

Research output: Contribution to journalArticle

Abstract

A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.

Original languageEnglish (US)
Pages (from-to)1299-1304
Number of pages6
JournalCirculation
Volume59
Issue number6
StatePublished - 1979
Externally publishedYes

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Mitral Valve Prolapse
Muscular Dystrophies
Duchenne Muscular Dystrophy
General Hospitals
Incidence

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Biddison, J. H., Dembo, D. H., Spalt, H., Hayes, M. G., & LeDoux, C. W. (1979). Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy. Circulation, 59(6), 1299-1304.

Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy. / Biddison, J. H.; Dembo, D. H.; Spalt, H.; Hayes, M. G.; LeDoux, C. W.

In: Circulation, Vol. 59, No. 6, 1979, p. 1299-1304.

Research output: Contribution to journalArticle

Biddison, JH, Dembo, DH, Spalt, H, Hayes, MG & LeDoux, CW 1979, 'Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy', Circulation, vol. 59, no. 6, pp. 1299-1304.
Biddison JH, Dembo DH, Spalt H, Hayes MG, LeDoux CW. Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy. Circulation. 1979;59(6):1299-1304.
Biddison, J. H. ; Dembo, D. H. ; Spalt, H. ; Hayes, M. G. ; LeDoux, C. W. / Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy. In: Circulation. 1979 ; Vol. 59, No. 6. pp. 1299-1304.
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