Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy

J. H. Biddison, D. H. Dembo, H. Spalt, M. G. Hayes, C. W. LeDoux

Research output: Contribution to journalArticle

Abstract

A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dystrophy Clinic. In addition, seven carriers of Duchenne and X-linked benign (Becker) dystrophy had evidence of MVP. Autosomal dominant transmission of MVP was present in four families. The unusually high prevalence of MVP in families with X-linked muscular dystrophy may have potential value in the recognition of the carrier trait.

Original languageEnglish (US)
Pages (from-to)1299-1304
Number of pages6
JournalUnknown Journal
Volume59
Issue number6
DOIs
StatePublished - Jan 1 1979

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Biddison, J. H., Dembo, D. H., Spalt, H., Hayes, M. G., & LeDoux, C. W. (1979). Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy. Unknown Journal, 59(6), 1299-1304. https://doi.org/10.1161/01.CIR.59.6.1299