Abstract
Horizontal gaze palsy with progressive scoliosis (HGPS) is a rare, autosomal recessive disorder characterized by a congenital absence of conjugate horizontal eye movement, with progressive scoliosis developing in childhood or adolescence. The authors identified two unrelated consanguineous families with HGPS. Genomewide homozygosity mapping and linkage analysis mapped the disease locus to a 30-cM interval on chromosome 11q23-25 (combined maximum multipoint lod score Z = 5.46).
Original language | English (US) |
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Pages (from-to) | 432-435 |
Number of pages | 4 |
Journal | Neurology |
Volume | 59 |
Issue number | 3 |
DOIs | |
State | Published - Aug 13 2002 |
Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology