False-Positive Complement-Fixation Serology in Histoplasmosis: A Retrospective Study

Peter Browne Terry, Edward C. Rosenow, Glenn D. Roberts

Research output: Contribution to journalArticle

Abstract

A review of the records of 79 consecutive patients who had a positive immunodiffusion or complement-fixation test for histoplasmosis showed 28 (35%) with false-positive serologic results in relation to their clinical significance. Twelve patients (15%) had complement-fixation titers of 1:32 or greater, without cultural or histological evidence of active infection. No common clinical or laboratory finding could be correlated with the presence of false-positive tests. The latter finding correlates well with the incidence of false-positive complement-fixation titers (12%) in the normal random patient population. (JAMA 239:2453-2456, 1978).

Original languageEnglish (US)
Pages (from-to)2453-2456
Number of pages4
JournalJAMA: The Journal of the American Medical Association
Volume239
Issue number23
DOIs
StatePublished - Jun 9 1978
Externally publishedYes

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Histoplasmosis
Serology
Retrospective Studies
Complement Fixation Tests
Immunodiffusion
Incidence
Infection
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

False-Positive Complement-Fixation Serology in Histoplasmosis : A Retrospective Study. / Terry, Peter Browne; Rosenow, Edward C.; Roberts, Glenn D.

In: JAMA: The Journal of the American Medical Association, Vol. 239, No. 23, 09.06.1978, p. 2453-2456.

Research output: Contribution to journalArticle

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