Falls and age in patients with Alzheimer's disease

Medhat M. Bassiony, Adam Rosenblatt, Alva Baker, Martin Steinberg, Cynthia D. Steele, Jeanie Marie E. Sheppard, Constantine G. Lyketsos

Research output: Contribution to journalArticlepeer-review

Abstract

The study's objective was to estimate the prevalence of falls in community-residing patients with Alzheimer's disease (AD) and to investigate the relationship between falls and age in AD. This was a study of 326 community-residing patients with AD according to National Institute of Neurological and Communicative Disorders and Stroke and Alzheimer's Disease and Related Disorders Association criteria. The patients and their caregivers were asked about falls, behavioral disturbances, and medication use within the last 2 weeks. The patients were also rated on standardized measures of cognitive impairment, stage of dementia, depression, daily activities, general health, and extrapyramidal symptoms. Falls occurred in 24 (7.4%) patients with AD during the last 2 weeks. Using multiple logistic regression analyses, falls were independently associated with old age (odds ratio = 1.2; p = .03; 95% confidence interval = 1.0 to 1.4) but not with other variables examined. The authors conclude that falls in community-residing patients with AD are significantly associated with old age. Population-based prospective studies are needed to investigate further the risk factors for falls in AD.

Original languageEnglish (US)
Pages (from-to)570-572
Number of pages3
JournalJournal of Nervous and Mental Disease
Volume192
Issue number8
DOIs
StatePublished - Aug 1 2004

Keywords

  • Alzheimer's disease
  • Dementia
  • Falls
  • Risk factors

ASJC Scopus subject areas

  • Psychiatry and Mental health

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