Failure of low molecular weight dextrans to alter the frequency of lung metastasis. Report on the V2 carcinoma of the rabbit

Sumner Wood, R. Robinson Baker, Jo H. Johnson

Research output: Contribution to journalArticle

Abstract

Three fractions of low molecular weight dextran (10,000, 40,000 and 70,000) were administered intravenously to Laboratory Lop rabbits before or after intravenous inoculation of ascitic V2 carcinoma cells. The frequency of pulmonary metastases was unaltered by dextran treatment. No extrapulmonary tumor was found in any instance. These findings are discussed in relation to the studies of other investigators and the need for additional experiments employing a variety of tumors and hosts is emphasized.

Original languageEnglish (US)
Pages (from-to)281-285
Number of pages5
JournalCancer
Volume20
Issue number2
DOIs
StatePublished - 1967

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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