Factors influencing nerve regeneration in a trial of timcodar dimesylate

M. Polydefkis; M. Sirdofsky; P. Hauer; B. G. Petty; B. Murinson; J. C. McArthur

doi:10.1212/01.wnl.0000194209.37604.57

Factors influencing nerve regeneration in a trial of timcodar dimesylate

M. Polydefkis, M. Sirdofsky, P. Hauer, B. G. Petty, B. Murinson, J. C. McArthur

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

The authors assessed the ability of the neurophilin compound, timcodar dimesylate, to accelerate the return of epidermal nerve fiber density (ENFD) after a standardized nerve injury in a randomized double blind, placebo controlled trial. While there was no difference in the regeneration rate between the treatment and placebo arms, the baseline ENFD (p = 0.006), height (p = 0.02), and race (p = 0.03) were associated with the regeneration rate.

Original language	English (US)
Pages (from-to)	259-261
Number of pages	3
Journal	Neurology
Volume	66
Issue number	2
DOIs	https://doi.org/10.1212/01.wnl.0000194209.37604.57
State	Published - Jan 2006

ASJC Scopus subject areas

Clinical Neurology

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abstract = "The authors assessed the ability of the neurophilin compound, timcodar dimesylate, to accelerate the return of epidermal nerve fiber density (ENFD) after a standardized nerve injury in a randomized double blind, placebo controlled trial. While there was no difference in the regeneration rate between the treatment and placebo arms, the baseline ENFD (p = 0.006), height (p = 0.02), and race (p = 0.03) were associated with the regeneration rate.",

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note = "Funding Information: Supported by grants NS41374 (MP) and RR00522 (GCRC JHU) from the National Institutes of Health, the Juvenile Diabetes Research Foundation (MP), and Vertex Pharmaceuticals Inc. ",

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AU - Murinson, B.

AU - McArthur, J. C.

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Factors influencing nerve regeneration in a trial of timcodar dimesylate

Abstract

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