Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Raimond L. Winslow; Dongming Cai; Ying Cheng Lai

Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Raimond L. Winslow, Dongming Cai, Ying Cheng Lai

School of Medicine

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

Original language	English (US)
Pages (from-to)	560-569
Number of pages	10
Journal	Proceedings of the ACM/IEEE Supercomputing Conference
State	Published - Dec 1 1994
Event	Proceedings of the 1994 Supercomputing Conference - Washington, DC, USA Duration: Nov 14 1994 → Nov 18 1994

ASJC Scopus subject areas

Electrical and Electronic Engineering

Cite this

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title = "Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node",

abstract = "Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.",

author = "Winslow, {Raimond L.} and Dongming Cai and Lai, {Ying Cheng}",

year = "1994",

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language = "English (US)",

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journal = "Proceedings of the ACM/IEEE Supercomputing Conference",

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T1 - Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

AU - Winslow, Raimond L.

AU - Cai, Dongming

AU - Lai, Ying Cheng

PY - 1994/12/1

Y1 - 1994/12/1

N2 - Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

AB - Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

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M3 - Conference article

AN - SCOPUS:0028748517

SN - 1063-9535

SP - 560

EP - 569

JO - Proceedings of the ACM/IEEE Supercomputing Conference

JF - Proceedings of the ACM/IEEE Supercomputing Conference

T2 - Proceedings of the 1994 Supercomputing Conference

Y2 - 14 November 1994 through 18 November 1994

ER -

Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Abstract

ASJC Scopus subject areas

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