Factors associated with willingness to provide biospecimens for genetics research among African American cancer survivors

Altovise T. Ewing, Nnenna Kalu, Gloria Cain, Lori Ann Hamby Erby, Luisel J. Ricks-Santi, Eva Tetteyfio-Kidd Telemaque, Denise M. Scott

Research output: Contribution to journalArticle

Abstract

This study evaluated factors associated with willingness to provide biospecimens for cancer genetic research among African American cancer survivors. A total of 200 African American adults diagnosed with breast, colon, and/or prostate cancers completed a self-administered survey. Family history information, beliefs about cancer research, cancer genetics and disparities knowledge, willingness to provide a biospecimen, and demographics were obtained. Chi-square, independent samples t tests, and logistic regression analyses were performed. Overall, 79% of this sample was willing to provide a biospecimen for cancer genetics research. Independent associations of willingness to provide a biospecimen existed among demographics (males (p = 0.041)), those who believed in the importance of genetic causes of cancer (p < 0.001), individuals who believe it is important to participate in genetics research (p < 0.001), and those who indicated they would participate in genetics research to help future generations (p = 0.026). Overall, 12.5–56% of participants demonstrated some level of genetics and cancer disparities. This study identified factors that may be incorporated into future research interventions to engage the African American cancer population in cancer genetics biobanking research.

Original languageEnglish (US)
JournalJournal of Community Genetics
DOIs
StatePublished - Jan 1 2019

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Genetic Research
African Americans
Survivors
Neoplasms
Demography
Social Responsibility
Colonic Neoplasms
Prostatic Neoplasms
Logistic Models
Regression Analysis
Breast Neoplasms

Keywords

  • African American cancer survivors
  • Biospecimens
  • Cancer genetics research
  • Cancer health disparities
  • Willingness to participate

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Genetics(clinical)

Cite this

Factors associated with willingness to provide biospecimens for genetics research among African American cancer survivors. / Ewing, Altovise T.; Kalu, Nnenna; Cain, Gloria; Erby, Lori Ann Hamby; Ricks-Santi, Luisel J.; Tetteyfio-Kidd Telemaque, Eva; Scott, Denise M.

In: Journal of Community Genetics, 01.01.2019.

Research output: Contribution to journalArticle

Ewing, Altovise T. ; Kalu, Nnenna ; Cain, Gloria ; Erby, Lori Ann Hamby ; Ricks-Santi, Luisel J. ; Tetteyfio-Kidd Telemaque, Eva ; Scott, Denise M. / Factors associated with willingness to provide biospecimens for genetics research among African American cancer survivors. In: Journal of Community Genetics. 2019.
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abstract = "This study evaluated factors associated with willingness to provide biospecimens for cancer genetic research among African American cancer survivors. A total of 200 African American adults diagnosed with breast, colon, and/or prostate cancers completed a self-administered survey. Family history information, beliefs about cancer research, cancer genetics and disparities knowledge, willingness to provide a biospecimen, and demographics were obtained. Chi-square, independent samples t tests, and logistic regression analyses were performed. Overall, 79{\%} of this sample was willing to provide a biospecimen for cancer genetics research. Independent associations of willingness to provide a biospecimen existed among demographics (males (p = 0.041)), those who believed in the importance of genetic causes of cancer (p < 0.001), individuals who believe it is important to participate in genetics research (p < 0.001), and those who indicated they would participate in genetics research to help future generations (p = 0.026). Overall, 12.5–56{\%} of participants demonstrated some level of genetics and cancer disparities. This study identified factors that may be incorporated into future research interventions to engage the African American cancer population in cancer genetics biobanking research.",
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