TY - JOUR
T1 - Factors associated with tuberculosis as an AIDS-defining disease in an immigration setting
AU - Martín, Vicente
AU - de Olalla, Patricia García
AU - Orcau, Angels
AU - Caylà, Joan A.
N1 - Funding Information:
The authors gratefully acknowledge the financial support provided by University of Malaya under the grant IIRG002B-2020IISS.
PY - 2011
Y1 - 2011
N2 - Background: Immigration can affect the evolution of TB as an AIDS-defining disease (AIDS-TB). Methods: The Barcelona AIDS register for 1994-2005 was analyzed, and the global characteristics of AIDS-TB and AIDS-non-TB cases were compared. The Mantel-Haenszel test was used in the trend analysis, and logistic regression was used in the multivariate analysis. Results: Of the 3600 cases studied, 1130 had both AIDS and TB. A declining trend in AIDS-TB rates was observed in both sexes among both immigrants and native residents. The percentage of AIDS-TB was significantly higher among immigrants (P = 0.02). The number of cases among immigrants remained constant over the period of study, but decreased among native residents. The sociodemographic and immunological characteristics associated with TB were male sex, age younger than 36 years, inner city residence, a record of incarceration, greater than 200 CD4+ T-cells/mm3, injecting drug use, heterosexual sex, and immigration from Latin America, the Caribbean, or sub-Saharan Africa. Conclusions: The incidence of TB as an AIDS-defining disease decreased in Barcelona during a recent 10-year period in both native and immigrant populations. However, immigrants remain a high-risk group for AIDS-TB and should be targeted for surveillance and control of both diseases.
AB - Background: Immigration can affect the evolution of TB as an AIDS-defining disease (AIDS-TB). Methods: The Barcelona AIDS register for 1994-2005 was analyzed, and the global characteristics of AIDS-TB and AIDS-non-TB cases were compared. The Mantel-Haenszel test was used in the trend analysis, and logistic regression was used in the multivariate analysis. Results: Of the 3600 cases studied, 1130 had both AIDS and TB. A declining trend in AIDS-TB rates was observed in both sexes among both immigrants and native residents. The percentage of AIDS-TB was significantly higher among immigrants (P = 0.02). The number of cases among immigrants remained constant over the period of study, but decreased among native residents. The sociodemographic and immunological characteristics associated with TB were male sex, age younger than 36 years, inner city residence, a record of incarceration, greater than 200 CD4+ T-cells/mm3, injecting drug use, heterosexual sex, and immigration from Latin America, the Caribbean, or sub-Saharan Africa. Conclusions: The incidence of TB as an AIDS-defining disease decreased in Barcelona during a recent 10-year period in both native and immigrant populations. However, immigrants remain a high-risk group for AIDS-TB and should be targeted for surveillance and control of both diseases.
KW - AIDS
KW - Epidemiology
KW - Immigration
KW - Tuberculosis
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U2 - 10.2188/jea.JE20100072
DO - 10.2188/jea.JE20100072
M3 - Article
C2 - 21325728
AN - SCOPUS:79953091083
SN - 0917-5040
VL - 21
SP - 108
EP - 113
JO - Journal of Epidemiology
JF - Journal of Epidemiology
IS - 2
ER -