Factors associated with osteoarthritis of the hand in males: Data from the baltimore longitudinal study of aging

Marc C. Hochberg, Margaret Lethbridge-cejku, Chris C. Plato, Fredrick Wigley, Jordan D. Tobin

Research output: Contribution to journalArticle

Abstract

The association of metabolic and physiologic factors with hand osteoarthritis was studied in 888 Caucasian male subjects aged 17-102 years in the Baltimore Longitudinal Study of Aging. Left-hand radiographs taken between 1958 and 1975 were read by one investigator for grade of osteoarthritis using Kellgren-Lawrence scales. Possible risk factors, assessed at the same visit as the last radiograph during this interval, included age and measures of bone mass, body composition, muscle mass, and muscle strength. Results of bivariate analyses of these cross-sectional data showed that increasing grade of hand osteoarthritis was associated with increasing age; greater mean levels of waist/hip ratio and percentage of body fat; and lower mean levels of percentage of cortical area, grip strength, and forearm circumference. After adjustment for age using residuals from best-fit quadratic regression models, none of these independent variables remained significantly associated with grade of hand osteoarthritis. These data fail to support hypotheses that metabolic and physiologic factors are associated with hand osteoarthritis independent of their known age-related changes. Am J Epidemiol 1991 ;134:1121-7.

Original languageEnglish (US)
Pages (from-to)1121-1127
Number of pages7
JournalAmerican Journal of Epidemiology
Volume134
Issue number10
StatePublished - Nov 15 1991

Fingerprint

Baltimore
Osteoarthritis
Longitudinal Studies
Hand
Waist-Hip Ratio
Muscle Strength
Hand Strength
Body Composition
Forearm
Adipose Tissue
Cross-Sectional Studies
Research Personnel
Bone and Bones
Muscles

Keywords

  • Obesity
  • Osteoarthritis
  • Osteoporosis
  • Risk factors

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

Cite this

Factors associated with osteoarthritis of the hand in males : Data from the baltimore longitudinal study of aging. / Hochberg, Marc C.; Lethbridge-cejku, Margaret; Plato, Chris C.; Wigley, Fredrick; Tobin, Jordan D.

In: American Journal of Epidemiology, Vol. 134, No. 10, 15.11.1991, p. 1121-1127.

Research output: Contribution to journalArticle

Hochberg, Marc C. ; Lethbridge-cejku, Margaret ; Plato, Chris C. ; Wigley, Fredrick ; Tobin, Jordan D. / Factors associated with osteoarthritis of the hand in males : Data from the baltimore longitudinal study of aging. In: American Journal of Epidemiology. 1991 ; Vol. 134, No. 10. pp. 1121-1127.
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