Factors Associated with Increased In-Hospital Mortality among Children with Intracerebral Hemorrhage

Malik M. Adil, Adnan I. Qureshi, Lauren A. Beslow, Ahmed A. Malik, Lori C. Jordan

Research output: Contribution to journalArticle

Abstract

We assessed factors associated with mortality and potential targets for intervention in a large national sample of children with nontraumatic intracerebral hemorrhage. Using Healthcare Cost and Utilization Project Kids' Inpatient Database ICD-9-CM code 431 identified children aged 1 to 18 years with nontraumatic intracerebral hemorrhage in 2003, 2006 and 2009. Intracerebral hemorrhage was the primary diagnosis for 1172 children (ages 1-18 years) over the 3-year sample. Factors associated with mortality based on multivariable logistic regression included Hispanic ethnicity (odds ratio 1.9, 95% confidence interval 1.1-3.3), older age (11-18 vs 1-10 years, odds ratio 2.5, 95% confidence interval 1.3-5.0), coagulopathy (odds ratio 3.0, 95% confidence interval 1.6-6.0), and coma (odds ratio 9.0, 95% confidence interval 3.2-24.6). From 2003 to 2009, there was a non-significant decrease in mortality with a significant increase in length of stay from 9 to 11 days (P <.003). In children with intracerebral hemorrhage, coma and coagulopathy had the strongest association with mortality; coagulopathy is a potentially modifiable risk factor.

Original languageEnglish (US)
Pages (from-to)1024-1028
Number of pages5
JournalJournal of child neurology
Volume30
Issue number8
DOIs
StatePublished - Jul 22 2015
Externally publishedYes

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Keywords

  • child
  • intracerebral hemorrhage
  • mortality

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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