Factors associated with anaemia in HIV-infected individuals in southern India

R. Subbaraman, B. Devaleenal, P. Selvamuthu, T. Yepthomi, Sunil Solomon, K. H. Mayer, N. Kumarasamy

Research output: Contribution to journalArticle

Abstract

Anaemia accelerates disease progression and increases mortality among HIV-infected individuals. Few studies have characterized this problem in developing countries. Haemoglobin values of adults presenting to an HIV tertiary care center in India between 1996 and 2007 were collected (n = 6996). Multivariate logistic regression analysis was performed to examine associations among anaemia, HIV progression and co-morbidities. Overall, anaemia prevalence was 41%. Twenty percent of patients with CD4 counts .500 cells/mL were anaemic, compared with 64% of those with CD4 counts ,100 cells/mL (P, 0.001). In multivariate analysis, CD4 count ,100 cells/mL (odds ratio [OR]:5.0, confidence interval [CI]:4.0-6.3), underweight body mass index (OR:4.8, CI:3.6-6.5), female gender (OR:3.1, CI:2.8-3.6) and tuberculosis (TB) (OR:1.6, CI:1.4-1.8) were significantly associated with anaemia. In this setting, management of anaemia should focus on antiretroviral therapy, nutritional supplementation and TB control. The high anaemia prevalence among patients meeting criteria for antiretroviral therapy highlights the need for increased access to non-zidovudine nucleoside reverse transcriptase inhibitors in developing countries.

Original languageEnglish (US)
Pages (from-to)489-492
Number of pages4
JournalInternational Journal of STD and AIDS
Volume20
Issue number7
DOIs
StatePublished - Jul 2009
Externally publishedYes

Fingerprint

Anemia
India
HIV
CD4 Lymphocyte Count
Odds Ratio
Confidence Intervals
Developing Countries
Tuberculosis
Reverse Transcriptase Inhibitors
Thinness
Nucleosides
Tertiary Care Centers
Disease Progression
Hemoglobins
Body Mass Index
Multivariate Analysis
Logistic Models
Regression Analysis
Morbidity
Mortality

Keywords

  • Anaemia
  • HIV
  • India
  • Malnutrition
  • Resource-limited settings
  • Tuberculosis

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Subbaraman, R., Devaleenal, B., Selvamuthu, P., Yepthomi, T., Solomon, S., Mayer, K. H., & Kumarasamy, N. (2009). Factors associated with anaemia in HIV-infected individuals in southern India. International Journal of STD and AIDS, 20(7), 489-492. https://doi.org/10.1258/ijsa.2008.008370

Factors associated with anaemia in HIV-infected individuals in southern India. / Subbaraman, R.; Devaleenal, B.; Selvamuthu, P.; Yepthomi, T.; Solomon, Sunil; Mayer, K. H.; Kumarasamy, N.

In: International Journal of STD and AIDS, Vol. 20, No. 7, 07.2009, p. 489-492.

Research output: Contribution to journalArticle

Subbaraman, R, Devaleenal, B, Selvamuthu, P, Yepthomi, T, Solomon, S, Mayer, KH & Kumarasamy, N 2009, 'Factors associated with anaemia in HIV-infected individuals in southern India', International Journal of STD and AIDS, vol. 20, no. 7, pp. 489-492. https://doi.org/10.1258/ijsa.2008.008370
Subbaraman, R. ; Devaleenal, B. ; Selvamuthu, P. ; Yepthomi, T. ; Solomon, Sunil ; Mayer, K. H. ; Kumarasamy, N. / Factors associated with anaemia in HIV-infected individuals in southern India. In: International Journal of STD and AIDS. 2009 ; Vol. 20, No. 7. pp. 489-492.
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