Facilitation of human tobacco self administration by ethanol: a behavioral analysis

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Abstract

The effect of ethanol on the cigarette smoking of alcoholic subjects was studied in a residential laboratory. During daily 6 hr sessions, cigarettes were obtained either by request to the ward staff or by operation of a lever (fixed ratio 5 or 10). In a mixed sequence across days, sessions involved ingestion of either vehicle (orange juice) alone or vehicle plus ethanol (133.7 g). During ethanol sessions, the rate of cigarette smoking increased from 26% to 117% of vehicle levels. A series of control studies eliminated a number of potential behavioral mechanisms for the observed effect and indicated that the ethanol induced increase in cigarette smoking occurred under a variety of experimental conditions: (1) when smoking could not occur concurrently with ethanol or vehicle consumption; (2) when subjects were not allowed to socialize; (3) when ingestion of ethanol or vehicle was scheduled for a number of consecutive days; (4) when various doses of ethanol were administered under blind conditions. In control experiments, weighing unsmoked tobacco and counting the number of puffs per cigarette indicated the effect was not due to smoking less of each cigarette. The effect was not limited to the experimental sessions alone, since total daily smoking was higher on ethanol days than vehicle days.

Original languageEnglish (US)
Pages (from-to)279-292
Number of pages14
JournalJournal of the Experimental Analysis of Behavior
Volume25
Issue number3
StatePublished - 1976

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Self Administration
Tobacco
Ethanol
Smoking
Tobacco Products
Eating
Alcoholics

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Psychology(all)
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Cite this

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title = "Facilitation of human tobacco self administration by ethanol: a behavioral analysis",
abstract = "The effect of ethanol on the cigarette smoking of alcoholic subjects was studied in a residential laboratory. During daily 6 hr sessions, cigarettes were obtained either by request to the ward staff or by operation of a lever (fixed ratio 5 or 10). In a mixed sequence across days, sessions involved ingestion of either vehicle (orange juice) alone or vehicle plus ethanol (133.7 g). During ethanol sessions, the rate of cigarette smoking increased from 26{\%} to 117{\%} of vehicle levels. A series of control studies eliminated a number of potential behavioral mechanisms for the observed effect and indicated that the ethanol induced increase in cigarette smoking occurred under a variety of experimental conditions: (1) when smoking could not occur concurrently with ethanol or vehicle consumption; (2) when subjects were not allowed to socialize; (3) when ingestion of ethanol or vehicle was scheduled for a number of consecutive days; (4) when various doses of ethanol were administered under blind conditions. In control experiments, weighing unsmoked tobacco and counting the number of puffs per cigarette indicated the effect was not due to smoking less of each cigarette. The effect was not limited to the experimental sessions alone, since total daily smoking was higher on ethanol days than vehicle days.",
author = "Griffiths, {Roland R} and George Bigelow and I. Liebson",
year = "1976",
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pages = "279--292",
journal = "Journal of the Experimental Analysis of Behavior",
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T2 - a behavioral analysis

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AU - Bigelow, George

AU - Liebson, I.

PY - 1976

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N2 - The effect of ethanol on the cigarette smoking of alcoholic subjects was studied in a residential laboratory. During daily 6 hr sessions, cigarettes were obtained either by request to the ward staff or by operation of a lever (fixed ratio 5 or 10). In a mixed sequence across days, sessions involved ingestion of either vehicle (orange juice) alone or vehicle plus ethanol (133.7 g). During ethanol sessions, the rate of cigarette smoking increased from 26% to 117% of vehicle levels. A series of control studies eliminated a number of potential behavioral mechanisms for the observed effect and indicated that the ethanol induced increase in cigarette smoking occurred under a variety of experimental conditions: (1) when smoking could not occur concurrently with ethanol or vehicle consumption; (2) when subjects were not allowed to socialize; (3) when ingestion of ethanol or vehicle was scheduled for a number of consecutive days; (4) when various doses of ethanol were administered under blind conditions. In control experiments, weighing unsmoked tobacco and counting the number of puffs per cigarette indicated the effect was not due to smoking less of each cigarette. The effect was not limited to the experimental sessions alone, since total daily smoking was higher on ethanol days than vehicle days.

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