Facile synthesis of new L-arginine derivatives as substrates for trypsin-like proteases

Yongjun Gao, Yuan C. Lee

Research output: Contribution to journalArticlepeer-review

Abstract

Facile and efficient synthetic routes for fluorogenic anilides of L-arginine have been developed. The amide bond formation uses phosphorous oxychloride as a condensing agent. The synthesis is simple, rapid, and affords excellent yields.

Original languageEnglish (US)
Pages (from-to)3465-3471
Number of pages7
JournalSynthetic Communications
Volume34
Issue number19
DOIs
StatePublished - Oct 25 2004

Keywords

  • 2-Aminobenzoic acid
  • Fluorogenic substrates
  • Synthesis
  • Trypsin

ASJC Scopus subject areas

  • Organic Chemistry

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