Fabrication of nanostructures of poly(ethylene glycol) and its application to protein adsorption and cell adhesion

Pilnam Kim, Deok Ho Kim, Byungkyu Kim, Seung Kyu Choi, Sang Ho Lee, Ali Khademhosseinid, Robert Langer, Kahp Y. Suh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We developed a method for fabricating poly(ethylene glycol) (PEG) nanostructures using capillary lithography mediated UV exposure. In comparison to unstructured, planar PEG films, the hydrophobicity was enhanced on PEG nanostructures presumably due to embedded air in the nanostructures. Proteins and cells were tested to examine the effects of the modification of surface properties on protein adsorption and cell adhesion.

Original languageEnglish (US)
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
Subtitle of host publication9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages767-769
Number of pages3
ISBN (Print)0974361119, 9780974361116
StatePublished - 2005
Externally publishedYes
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: Oct 9 2005Oct 13 2005

Publication series

NameMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume1

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
CountryUnited States
CityBoston, MA
Period10/9/0510/13/05

Keywords

  • Capillary lithograpy
  • Cell adhesion
  • Nanotopography
  • PEG
  • Protein

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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