Eyelid involvement in paracoccidioidomycosis

Antonio A.V. Cruz, Fabio Zenha, Jose T. Silva, Roberto Martinez

Research output: Contribution to journalReview article


Purpose: To describe a series of patients with eyelid lesions caused by paracoccidioidomycosis and to estimate the prevalence of eyelid involvement in this disease. Methods: The medical records of 439 patients with paracoccidioidomycosis admitted to our hospital from 1992 to 2002 were reviewed. Age, sex, and clinical forms of the disease were recorded. All patients with eyelid involvement had a skin biopsy positive for paracoccidioidomycosis and were examined by an ophthalmologist with oculoplastic training. Results: Of 439 patients with acute, subacute, or chronic paracoccidioidomycosis, 11 (2.5%) had eyelid involvement. Active lesions ranged from erythematous patches of madarosis to frank destructive ulcers indistinguishable from malignancies. Healed lesions were characterized by a high degree of fibrosis. Cicatricial changes induced eyelid malpositions (entropion or ectropion) and fusion of eyelid tissues to the globe. Madarosis was a constant finding in the inactive lesions. Conclusions: The prevalence of eyelid involvement in paracoccidioidomycosis is low. Isolated active lesions are usually diagnosed as malignant tumors. Cicatricial changes are characterized by a high degree of fibrosis. If not treated, the mycosis can destroy the eyelid.

Original languageEnglish (US)
Pages (from-to)212-216
Number of pages5
JournalOphthalmic plastic and reconstructive surgery
Issue number3
StatePublished - May 1 2004

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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