TY - JOUR
T1 - Extracorporeal life support for a 5-week-old infant with idiopathic pulmonary hemosiderosis
AU - Gutierrez, Sherrill
AU - Shaw, Susanna
AU - Huseni, Shehlanoor
AU - Sachdeva, Shagun
AU - Costello, John P.
AU - Basu, Sonali
AU - Nath, Dilip S.
AU - Klugman, Darren
N1 - Publisher Copyright:
© 2013, Springer-Verlag Berlin Heidelberg.
PY - 2014/12
Y1 - 2014/12
N2 - Idiopathic pulmonary hemosiderosis is a rare disease defined by the triad of iron deficiency anemia, hemoptysis, and diffuse pulmonary infiltrates on chest radiograph. Idiopathic pulmonary hemosiderosis is known to cause dyspnea and, in some cases, acute onset of massive pulmonary hemorrhage which is traditionally treated with conventional mechanical ventilation or high-frequency oscillation in conjunction with immunosuppressive therapy. In this case report, we describe a 5-week-old infant presenting with hemoptysis, massive pulmonary hemorrhage, and significant hypercapnic respiratory failure. The patient failed conventional ventilation but responded well to extracorporeal life support that was initiated early in his course. Idiopathic pulmonary hemosiderosis was suspected in light of his response to high-dose steroids and was confirmed by subsequent lung biopsies. Conclusion: Patients with severe pulmonary hemorrhage secondary to idiopathic pulmonary hemosiderosis can be safely supported with extracorporeal life support when conventional therapies have been exhausted.
AB - Idiopathic pulmonary hemosiderosis is a rare disease defined by the triad of iron deficiency anemia, hemoptysis, and diffuse pulmonary infiltrates on chest radiograph. Idiopathic pulmonary hemosiderosis is known to cause dyspnea and, in some cases, acute onset of massive pulmonary hemorrhage which is traditionally treated with conventional mechanical ventilation or high-frequency oscillation in conjunction with immunosuppressive therapy. In this case report, we describe a 5-week-old infant presenting with hemoptysis, massive pulmonary hemorrhage, and significant hypercapnic respiratory failure. The patient failed conventional ventilation but responded well to extracorporeal life support that was initiated early in his course. Idiopathic pulmonary hemosiderosis was suspected in light of his response to high-dose steroids and was confirmed by subsequent lung biopsies. Conclusion: Patients with severe pulmonary hemorrhage secondary to idiopathic pulmonary hemosiderosis can be safely supported with extracorporeal life support when conventional therapies have been exhausted.
KW - ECMO
KW - Extracorporeal life support
KW - Extracorporeal membrane oxygenation
KW - Idiopathic pulmonary hemosiderosis
KW - Pediatric critical care
KW - Pulmonary hemorrhage
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U2 - 10.1007/s00431-013-2130-4
DO - 10.1007/s00431-013-2130-4
M3 - Article
C2 - 23942745
AN - SCOPUS:84881265730
SN - 0340-6199
VL - 173
SP - 1573
EP - 1576
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 12
ER -