Extracellular vesicles in immunomodulation and tumor progression

Carolyn Marar; Bartholomew Starich; Denis Wirtz

doi:10.1038/s41590-021-00899-0

Extracellular vesicles in immunomodulation and tumor progression

Carolyn Marar, Bartholomew Starich, Denis Wirtz

Whiting School of Engineering

Research output: Contribution to journal › Review article › peer-review

Abstract

Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as mediators of communication between cancer and immune cells. This expanded role of EVs may shed light on the mechanisms behind tumor progression and provide translational diagnostic and prognostic tools for immunologists.

Original language	English (US)
Pages (from-to)	560-570
Number of pages	11
Journal	Nature Immunology
Volume	22
Issue number	5
DOIs	https://doi.org/10.1038/s41590-021-00899-0
State	Published - May 2021

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1038/s41590-021-00899-0

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title = "Extracellular vesicles in immunomodulation and tumor progression",

abstract = "Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as mediators of communication between cancer and immune cells. This expanded role of EVs may shed light on the mechanisms behind tumor progression and provide translational diagnostic and prognostic tools for immunologists.",

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Extracellular vesicles in immunomodulation and tumor progression

Abstract

ASJC Scopus subject areas

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