Extracellular vesicles in immunomodulation and tumor progression

Carolyn Marar, Bartholomew Starich, Denis Wirtz

Research output: Contribution to journalReview articlepeer-review


Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as mediators of communication between cancer and immune cells. This expanded role of EVs may shed light on the mechanisms behind tumor progression and provide translational diagnostic and prognostic tools for immunologists.

Original languageEnglish (US)
Pages (from-to)560-570
Number of pages11
JournalNature Immunology
Issue number5
StatePublished - May 2021

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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