Extracellular vesicles for research on psychiatric disorders

Shin Ichi Kano, Eisuke Dohi, Indigo V.L. Rose

Research output: Contribution to journalArticlepeer-review

Abstract

Extracellular vesicles (EVs) have gained increasing attention as underexplored intercellular communication mechanisms in basic science and as potential diagnostic tools in translational studies, particularly those related to cancers and neurological disorders. This article summarizes accumulated findings in the basic biology of EVs, EV research methodology, and the roles of EVs in brain cell function and dysfunction, as well as emerging EV studies in human brain disorders. Further research on EVs in neurobiology and psychiatry may open the door to a better understanding of intercellular communications in healthy and diseased brains, and the discovery of novel biomarkers and new therapeutic strategies in psychiatric disorders.

Original languageEnglish (US)
Pages (from-to)7-16
Number of pages10
JournalSchizophrenia bulletin
Volume45
Issue number1
DOIs
StatePublished - Jan 1 2019

Keywords

  • Biomarker
  • EVs
  • Exosome
  • Extracellular vesicle
  • Intercellular communication
  • Microvesicle
  • Psychiatric disorders
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Extracellular vesicles for research on psychiatric disorders'. Together they form a unique fingerprint.

Cite this