External-beam radiotherapy for differentiated thyroid cancer locoregional control: A statement of the American Head and Neck Society

Ana P. Kiess, Nishant Agrawal, James D. Brierley, Umamaheswar Duvvuri, Robert L. Ferris, Eric Genden, Richard J. Wong, R. Michael Tuttle, Nancy Y. Lee, Gregory W. Randolph

Research output: Contribution to journalReview article

Abstract

The use of external-beam radiotherapy (EBRT) in differentiated thyroid cancer (DTC) is debated because of a lack of prospective clinical data, but recent retrospective studies have reported benefits in selected patients. The Endocrine Surgery Committee of the American Head and Neck Society provides 4 recommendations regarding EBRT for locoregional control in DTC, based on review of literature and expert opinion of the authors. (1) EBRT is recommended for patients with gross residual or unresectable locoregional disease, except for patients <45 years old with limited gross disease that is radioactive iodine (RAI)-avid. (2) EBRT should not be routinely used as adjuvant therapy after complete resection of gross disease. (3) After complete resection, EBRT may be considered in select patients >45 years old with high likelihood of microscopic residual disease and low likelihood of responding to RAI. (4) Cervical lymph node involvement alone should not be an indication for adjuvant EBRT.

Original languageEnglish (US)
Pages (from-to)493-498
Number of pages6
JournalHead and Neck
Volume38
Issue number4
DOIs
StatePublished - Apr 1 2016

Keywords

  • follicular
  • papillary
  • radiation
  • radiotherapy
  • thyroid cancer

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Kiess, A. P., Agrawal, N., Brierley, J. D., Duvvuri, U., Ferris, R. L., Genden, E., Wong, R. J., Tuttle, R. M., Lee, N. Y., & Randolph, G. W. (2016). External-beam radiotherapy for differentiated thyroid cancer locoregional control: A statement of the American Head and Neck Society. Head and Neck, 38(4), 493-498. https://doi.org/10.1002/hed.24357