Extent of pelvic lymph node dissection during radical cystectomy: is bigger better?

Debasish Sundi, Robert S. Svatek, Matthew E. Nielsen, Mark P. Schoenberg, Trinity Bivalacqua

Research output: Contribution to journalReview article

Abstract

Pelvic lymph node dissection (PLND) is a standard component of radical cystectomy (RC) for bladder cancer. The optimal anatomic PLND template remains undefined. An extended PLND template can potentially improve survival through the eradication of micrometastatic disease and improved pathologic staging. However, this benefit could be compromised by a potential increase in perioperative complications and cost. Two randomized controlled clinical trials that will clarify this question are ongoing. Many important retrospective studies have provided insights into the optimal PLND extent. Here the authors review the key evidence that informs how urologists may tailor the PLND template during RC depending on patient and tumor characteristics.

Original languageEnglish (US)
Pages (from-to)159-166
Number of pages8
JournalReviews in urology
Volume16
Issue number4
StatePublished - Jan 1 2014

Keywords

  • Micrometastatic disease
  • Pelvic lymph node dissection
  • Radical cystectomy
  • Template

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  • Cite this

    Sundi, D., Svatek, R. S., Nielsen, M. E., Schoenberg, M. P., & Bivalacqua, T. (2014). Extent of pelvic lymph node dissection during radical cystectomy: is bigger better? Reviews in urology, 16(4), 159-166.