Abstract
We studied the expression of various cell surface molecules (CD25, CD28, CD29, CD45RO, CD56, LFA-1, VLA-4) on peripheral blood CD4+ T-cells in 6 relapsing-remitting multiple sclerosis (RR-MS) patients. Furthermore, changes in the expression pattern of these surface markers during intervals of increased disease activity, which was measured by gadolinium (Gd-DTPA) magnetic resonance imaging (MRI) were examined. Although several patients showed signs of increased disease activity during the observation period, this was not paralleled by a relevant change in the expression of these activation and adhesion molecules.
Original language | English (US) |
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Pages (from-to) | 147-151 |
Number of pages | 5 |
Journal | Journal of Neuroimmunology |
Volume | 66 |
Issue number | 1-2 |
DOIs | |
State | Published - May 1996 |
Externally published | Yes |
Keywords
- fluorescence activated cell sorting (FACS)
- lymphocyte subsets
- magnetic resonance imaging (MRI)
- multiple sclerosis
ASJC Scopus subject areas
- Immunology
- Clinical Neurology
- Immunology and Allergy
- Neurology