Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens

S. E. Valone, E. A. Rich, R. S. Wallis, J. J. Ellner

Research output: Contribution to journalArticlepeer-review

Abstract

Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the presence of polymyxin B.

Original languageEnglish (US)
Pages (from-to)3313-3315
Number of pages3
JournalInfection and Immunity
Volume56
Issue number12
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

Fingerprint Dive into the research topics of 'Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens'. Together they form a unique fingerprint.

Cite this