Abstract
Four mycobacterial preparations directly stimulated human blood monocytes and alveolar macrophages to produce tumor necrosis factor (TNF). Monoclonal antibody against TNF blocked (99%) TNF activity. Lipopolysaccharide was not responsible for the TNF activity generated; activity was unaffected in the presence of polymyxin B.
Original language | English (US) |
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Pages (from-to) | 3313-3315 |
Number of pages | 3 |
Journal | Infection and Immunity |
Volume | 56 |
Issue number | 12 |
State | Published - 1988 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology