Exposición al humo de tabaco y concentración de cotinina en la saliva en una muestra de escolares de Barcelona

Translated title of the contribution: Exposure to environmental tobacco smoke and salivary cotinine concentration in a sample of students from Barcelona, Spain

Carles Ariza, Anna Schiaffino, José Antonio Pascual, Jorge Twose, Manuel Nebot, Esteve Fernández

Research output: Contribution to journalArticle


Background and objective: The objective of this study was to assess the exposure to environmental tobacco smoke (ETS) by means of the concentration of salivary cotinine in a sample of adolescent students, and its relationship with active and passive tobacco consumption. Methods: A cross-sectional survey was conducted in 92 secondary education and high school pupils (16-20 years). Salivary samples were collected and salivary cotinine was measured by gas chromatography/mass spectrometry. Salivary cotinine medians and interquartile ranges were calculated. Significant statistical differences were detected with the non parametric test for medians. Results: The median of salivary cotinine concentration in current smokers was 91.5ng/ml (RI: 62,4-125); in former smokers 7.9 ng/ml (RI: 5,1-15,5) and in never smokers 1.9 ng/ml (RI: 0-3,6). In smokers of more than 10 cigarettes per day, the result was 98.3 ng/ml (RI:63,4-142,9). Among non-smokers (never-smoker and ex-smokers), the median of salivary cotinine in non-smokers living with smokers was 3.3 ng/ml (RI: 0-8,6) versus 2.9 ng/ml (RI: 1,1-6,9) in those living with non-smokers. Conclusions: The salivary cotinine concentration increases with the intensity of tobacco consumption and the perception of passive exposure to tobacco smoke.

Original languageSpanish
Pages (from-to)622-625
Number of pages4
JournalMedicina clinica
Issue number16
StatePublished - Oct 31 2009



  • Adolescence
  • Cotinine
  • Passive exposure to tobacco smoke
  • Passive smoking
  • Smoking

ASJC Scopus subject areas

  • Medicine(all)

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