Exposure-time dependence of the threshold for ultrasonically induced murine lung hemorrhage

Carol H. Raeman; S. Z. Child; D. Dalecki; C. Cox; E. L. Carstensen

doi:10.1016/0301-5629(95)02036-5

Exposure-time dependence of the threshold for ultrasonically induced murine lung hemorrhage

Carol H. Raeman, S. Z. Child, D. Dalecki, C. Cox, E. L. Carstensen

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

Although the extent of suprathreshold damage to murine lung that results from exposure to pulsed ultrasound increases with time, the threshold level for lung hemorrhage is relatively insensitive to total exposure time. Adult mice were exposed for 20 s and 3 min to 2.3-MHz ultrasound (10-μs pulses, 100-Hz pulse repetition frequency) at peak positive pressures ranging up to 3 MPa. Threshold pressures for the two exposure times, 1.6 MPa and 1.4 MPa, respectively, are the same within the statistical significance of the measurements.

Original language	English (US)
Pages (from-to)	139-141
Number of pages	3
Journal	Ultrasound in Medicine and Biology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/0301-5629(95)02036-5
State	Published - 1996
Externally published	Yes

Keywords

Bioeffects
Lung hemorrhage
Mice
Pulsed ultrasound

ASJC Scopus subject areas

Biophysics
Radiological and Ultrasound Technology
Acoustics and Ultrasonics

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10.1016/0301-5629(95)02036-5

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abstract = "Although the extent of suprathreshold damage to murine lung that results from exposure to pulsed ultrasound increases with time, the threshold level for lung hemorrhage is relatively insensitive to total exposure time. Adult mice were exposed for 20 s and 3 min to 2.3-MHz ultrasound (10-μs pulses, 100-Hz pulse repetition frequency) at peak positive pressures ranging up to 3 MPa. Threshold pressures for the two exposure times, 1.6 MPa and 1.4 MPa, respectively, are the same within the statistical significance of the measurements.",

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AU - Raeman, Carol H.

AU - Child, S. Z.

AU - Dalecki, D.

AU - Cox, C.

AU - Carstensen, E. L.

PY - 1996

Y1 - 1996

N2 - Although the extent of suprathreshold damage to murine lung that results from exposure to pulsed ultrasound increases with time, the threshold level for lung hemorrhage is relatively insensitive to total exposure time. Adult mice were exposed for 20 s and 3 min to 2.3-MHz ultrasound (10-μs pulses, 100-Hz pulse repetition frequency) at peak positive pressures ranging up to 3 MPa. Threshold pressures for the two exposure times, 1.6 MPa and 1.4 MPa, respectively, are the same within the statistical significance of the measurements.

AB - Although the extent of suprathreshold damage to murine lung that results from exposure to pulsed ultrasound increases with time, the threshold level for lung hemorrhage is relatively insensitive to total exposure time. Adult mice were exposed for 20 s and 3 min to 2.3-MHz ultrasound (10-μs pulses, 100-Hz pulse repetition frequency) at peak positive pressures ranging up to 3 MPa. Threshold pressures for the two exposure times, 1.6 MPa and 1.4 MPa, respectively, are the same within the statistical significance of the measurements.

KW - Bioeffects

KW - Lung hemorrhage

KW - Mice

KW - Pulsed ultrasound

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Exposure-time dependence of the threshold for ultrasonically induced murine lung hemorrhage

Abstract

Keywords

ASJC Scopus subject areas

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