Exposure-time dependence of the threshold for ultrasonically induced murine lung hemorrhage

Carol H. Raeman, S. Z. Child, D. Dalecki, C. Cox, E. L. Carstensen

Research output: Contribution to journalArticlepeer-review

Abstract

Although the extent of suprathreshold damage to murine lung that results from exposure to pulsed ultrasound increases with time, the threshold level for lung hemorrhage is relatively insensitive to total exposure time. Adult mice were exposed for 20 s and 3 min to 2.3-MHz ultrasound (10-μs pulses, 100-Hz pulse repetition frequency) at peak positive pressures ranging up to 3 MPa. Threshold pressures for the two exposure times, 1.6 MPa and 1.4 MPa, respectively, are the same within the statistical significance of the measurements.

Original languageEnglish (US)
Pages (from-to)139-141
Number of pages3
JournalUltrasound in Medicine and Biology
Volume22
Issue number1
DOIs
StatePublished - Jan 1 1996
Externally publishedYes

Keywords

  • Bioeffects
  • Lung hemorrhage
  • Mice
  • Pulsed ultrasound

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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