Abstract
The weak absorption of near-infrared light by skin tissue has offered an important optical window for diagnostic possibilities with optical means including optical biopsy. The strong scattering of the near-infrared light by skin tissue, however, presents a great challenge to the modeling of light propagation through and the optical measurement of the tissue. We have measured transmittance and reflectance of fresh porcine skin and performed Monte Carlo simulations to inversely determine the absorption coefficient, scattering coefficient and asymmetric coefficient of tissue samples in the spectral range from 900 to 1500nm. The state of cellular integrity following optical measurements was verified using transmission electron microscopy (TEM). These results were correlated with the possible effects on the measurements of the tissue optical properties.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 184-191 |
| Number of pages | 8 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 3917 |
| State | Published - Jan 1 2000 |
| Externally published | Yes |
| Event | Optical Biopsy III - San Jose, CA, USA Duration: Jan 23 2000 → Jan 24 2000 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering