Experimental retinal vascular occlusion III - An ultrastructural study of simultaneous occlusion of central retinal vein and artery

Claudio P. Juarez, Mark O.M. Tso, Wichard A.J. van Heuven, Manmohindar Singh Hayreh, Sohan Singh Hayreh

Research output: Contribution to journalArticlepeer-review

Abstract

The retinal changes following the simultaneous occlusion of retinal vessels were examined at an ultrastructural level. The preservation of endothelial cells that prevented leakage of blood and horseradish peroxidase tracer material in the surrounding retinal tissues explained the lack of hemorrhages observed clinically. Mueller cell death resulted in severe structural disorganization of the retina, with disruption of the inner limiting membrane, involvement of the outer retinal layers, and fleurette formation. The retinal macrocysts were derived from ischemic infarction.

Original languageEnglish (US)
Pages (from-to)89-101
Number of pages13
JournalInternational Ophthalmology
Volume9
Issue number2-3
DOIs
StatePublished - May 1986
Externally publishedYes

Keywords

  • central retinal artery
  • central retinal vein
  • ischemia
  • retina
  • vascular occlusion

ASJC Scopus subject areas

  • Ophthalmology

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