Experimental retinal vascular occlusion II - A clinico-pathologic correlative study of simultaneous occlusion of central retinal vein and artery

Claudio P. Juarez, Mark O.M. Tso, Wichard A.J. van Heuven, Manmohindar Singh Hayreh, Sohan Singh Hayreh

Research output: Contribution to journalArticlepeer-review

Abstract

After experimentally occluding the central retinal vein and artery simultaneously at their point of entry into the optic nerve, acute retinal necrosis occurred, but not hemorrhagic retinopathy. In the retinal vasculature, stagnation of blood flow and thrombosis with subsequent recanalization was noted. The necrosis was extensive in the inner retinal layers but focal in the outer retinal layers. The internal limiting membrane was detached and disrupted in every case. Following the post-edematous stage, numerous micro and macroretinal cysts appeared. The peripheral retina showed much less ischemic changes. A clinico-pathologic correlation was made.

Original languageEnglish (US)
Pages (from-to)77-87
Number of pages11
JournalInternational Ophthalmology
Volume9
Issue number2-3
DOIs
StatePublished - May 1986

Keywords

  • central retinal artery
  • central retinal vein
  • ischemia
  • retina
  • vascular occlusion

ASJC Scopus subject areas

  • Ophthalmology

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