Abstract
Adult rabbit retinal vessels underwent neovascularization in response to tumor implantation within the vitreous body. The neovascular response was presumably elicited by the tumor angiogenesis factor (TAF). The response of adult retinal vessels to an angiogenic stimulus raises the possibility that a similar substance may cause retinal neovascularization in humans, and that in normal conditions the vitreous may be able to suppress angiogenic activity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 660-664 |
| Number of pages | 5 |
| Journal | American Journal of Ophthalmology |
| Volume | 83 |
| Issue number | 5 |
| State | Published - 1977 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Experimental retinal neovascularization induced by intravitreal tumors. / Finkelstein, Daniel; Brem, Steven; Patz, Arnall; Folkman, Judah; Miller, Stephen; Ho-Chen, Chung.
In: American Journal of Ophthalmology, Vol. 83, No. 5, 1977, p. 660-664.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Experimental retinal neovascularization induced by intravitreal tumors
AU - Finkelstein, Daniel
AU - Brem, Steven
AU - Patz, Arnall
AU - Folkman, Judah
AU - Miller, Stephen
AU - Ho-Chen, Chung
PY - 1977
Y1 - 1977
N2 - Adult rabbit retinal vessels underwent neovascularization in response to tumor implantation within the vitreous body. The neovascular response was presumably elicited by the tumor angiogenesis factor (TAF). The response of adult retinal vessels to an angiogenic stimulus raises the possibility that a similar substance may cause retinal neovascularization in humans, and that in normal conditions the vitreous may be able to suppress angiogenic activity.
AB - Adult rabbit retinal vessels underwent neovascularization in response to tumor implantation within the vitreous body. The neovascular response was presumably elicited by the tumor angiogenesis factor (TAF). The response of adult retinal vessels to an angiogenic stimulus raises the possibility that a similar substance may cause retinal neovascularization in humans, and that in normal conditions the vitreous may be able to suppress angiogenic activity.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017713458&partnerID=8YFLogxK
M3 - Article
C2 - 868966
AN - SCOPUS:0017713458
VL - 83
SP - 660
EP - 664
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 5
ER -