Experimental malaria: Effects upon the immune response to different antigens

Research output: Contribution to journalArticlepeer-review

Abstract

At the height of a malaria infection, mice were injected with either sheep erythrocytes (SRBCs) or phage particles, and the antibody response was followed. The response to SRBCs was com­pletely suppressed, but there was a normal re­sponse to phage particles, and antibody to the malaria parasites appeared. It is possible that the selective suppression of the response to SRBCs in infected mice was caused by impairment of the processing of other large particulate antigens or by depletion of the population of lymphoid cells sensitive to SRBCs.

Original languageEnglish (US)
Pages (from-to)99-101
Number of pages3
JournalJournal of Infectious Diseases
Volume123
Issue number1
DOIs
StatePublished - Jan 1971
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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