A model of herpetic keratitis with type I Herpesvirus hominis (HVH) was established in the guinea pig. Experimentally produced type I HVH infection in one eye evoked systemic immunity and produced significant protection against subsequent infections with type I HVH in both that eye and the fellow eye. The study emphasizes the species differences between the immune mechanisms of the guinea pig and the rabbit. The guinea pig appears to be better suited than the rabbit to the study of immunologic responses that control facultative intracellular corneal parasitism.
|Original language||English (US)|
|Number of pages||4|
|Journal||Canadian Journal of Ophthalmology|
|State||Published - 1974|
ASJC Scopus subject areas