@article{e46a5c0024cc492dac2e269e35782e41,
title = "Experience-dependent regulation of NG2 progenitors in the developing barrel cortex",
abstract = "We found that, during the formation of the mouse barrel cortex, NG2 cells received glutamatergic synapses from thalamocortical fibers and preferentially accumulated along septa separating the barrels. Sensory deprivation reduced thalamocortical inputs on NG2 cells and increased their proliferation, leading to a more uniform distribution in the deprived barrels. Thus, early sensory experience regulates thalamocortical innervation on NG2 cells, as well as their proliferation and distribution during development.",
author = "Mangin, {Jean Marie} and Peijun Li and Joseph Scafidi and Vittorio Gallo",
note = "Funding Information: We thank D. Bergles and M. Huntsman for discussion. We thank L.-J. Chew, J. Corbin, M. Huntsman and J. Liu for critically reading an earlier version of this manuscript. We thank E. Quinlan (University of Maryland) for her advice on the dark-rearing experiments. We also thank R. Chittajallu and J. Isaac for their help with the thalamocortical slice preparation. This work was supported by grants from the US National Institutes of Health (NIH; R01NS045702, R01NS056427) and NIH Intellectual and Developmental Disabilities Research Center (P30HD40677) to V.G., an NIH grant (K08NS073793) to J.S., and by Agence Nationale de la Recherche Jeune Chercheuse Jeune Chercheur Grant Oligospine (J.-M.M.).",
year = "2012",
month = sep,
doi = "10.1038/nn.3190",
language = "English (US)",
volume = "15",
pages = "1192--1194",
journal = "Nature Neuroscience",
issn = "1097-6256",
publisher = "Nature Publishing Group",
number = "9",
}