Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities

Wei Li, Yongjun Dang, Jun O. Liu, Biao Yu

Research output: Contribution to journalArticlepeer-review

Abstract

Rapid access : An expeditious synthesis of hippuristanol was developed that allowed rapid access to a number of analogues with structural alteration at its E and F rings (see scheme), facilitating the structure-activity relationship studies of the novel inhibitor of eukaryotic translation initiation.

Original languageEnglish (US)
Pages (from-to)10356-10359
Number of pages4
JournalChemistry - A European Journal
Volume15
Issue number40
DOIs
StatePublished - Oct 12 2009

Keywords

  • Cancer
  • Natural products
  • Steroids
  • Structureactivity relationships

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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