Expanding the Menu of HIV Prevention Options

A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States

Deanna Kerrigan, Andrea Mantsios, R. Grant, M. Markowitz, P. Defechereux, M. la Mar, Sarah Beckham, P. Hammond, D. Margolis, M. Murray

Research output: Contribution to journal › Article

Abstract

Adherence challenges with oral pre-exposure prophylaxis have stimulated interest in alternate modes of administration including long-acting injections. We conducted 30 in-depth interviews with 26 male trial participants and 4 clinical providers in a Phase IIa study (ÉCLAIR) evaluating the use of long-acting cabotegravir (CAB-LA) injections in New York and San Francisco. Interviews exploring attitudes and experiences with CAB-LA were audiotaped, transcribed, and analyzed using thematic content analysis. Despite a high frequency of some level of side effects, almost all participants reported being interested in continuing with CAB-LA, versus a daily oral, due to its convenience and the perceived advantage of not worrying about adhering to pills. Providers reinforced the importance of CAB-LA as a prevention option and the need for guidelines to assist patient decision-making. Further research is needed on the acceptability of CAB-LA among men and women at higher risk for HIV in different settings.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalAIDS and Behavior
DOIs
StateAccepted/In press - Dec 30 2017

Fingerprint

HIV
Injections
Interviews
San Francisco
Decision Making
cellulose acetate-butyrate
Guidelines
Research

Keywords

  • HIV
  • Long-acting injectable
  • Men
  • PrEP
  • Providers
  • Qualitative
  • Risk behavior

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Expanding the Menu of HIV Prevention Options : A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States. / Kerrigan, Deanna; Mantsios, Andrea; Grant, R.; Markowitz, M.; Defechereux, P.; la Mar, M.; Beckham, Sarah; Hammond, P.; Margolis, D.; Murray, M.

In: AIDS and Behavior, 30.12.2017, p. 1-10.

Research output: Contribution to journal › Article

Kerrigan, D, Mantsios, A, Grant, R, Markowitz, M, Defechereux, P, la Mar, M, Beckham, S, Hammond, P, Margolis, D & Murray, M 2017, 'Expanding the Menu of HIV Prevention Options: A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States', AIDS and Behavior, pp. 1-10. https://doi.org/10.1007/s10461-017-2017-x
Kerrigan D, Mantsios A, Grant R, Markowitz M, Defechereux P, la Mar M et al. Expanding the Menu of HIV Prevention Options: A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States. AIDS and Behavior. 2017 Dec 30;1-10. https://doi.org/10.1007/s10461-017-2017-x
Kerrigan, Deanna ; Mantsios, Andrea ; Grant, R. ; Markowitz, M. ; Defechereux, P. ; la Mar, M. ; Beckham, Sarah ; Hammond, P. ; Margolis, D. ; Murray, M. / Expanding the Menu of HIV Prevention Options : A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States. In: AIDS and Behavior. 2017 ; pp. 1-10.
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