Expanding roles for SREBP in metabolism

Research output: Contribution to journalReview articlepeer-review


Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with the description of new regulatory mechanisms, the identification of unexpected transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer, immunity, neuroprotection, and autophagy.

Original languageEnglish (US)
Pages (from-to)414-419
Number of pages6
JournalCell Metabolism
Issue number4
StatePublished - Oct 3 2012

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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