Expanding roles for SREBP in metabolism

Research output: Contribution to journalArticle

Abstract

Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with the description of new regulatory mechanisms, the identification of unexpected transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer, immunity, neuroprotection, and autophagy.

Original languageEnglish (US)
Pages (from-to)414-419
Number of pages6
JournalCell Metabolism
Volume16
Issue number4
DOIs
StatePublished - Oct 3 2012

Fingerprint

Sterol Regulatory Element Binding Proteins
Lipogenesis
Autophagy
Type 2 Diabetes Mellitus
Immunity
Homeostasis
Transcription Factors
Lipids
Neoplasms
Neuroprotection

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Physiology

Cite this

Expanding roles for SREBP in metabolism. / Shao, Wei; Espenshade, Peter.

In: Cell Metabolism, Vol. 16, No. 4, 03.10.2012, p. 414-419.

Research output: Contribution to journalArticle

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