Exophiala werneckii endophthalmitis following cataract surgery in an immunocompetent individual

C. E. Huber, T. Laberge, T. Schwiesow, K. Carroll, P. S. Bernstein, N. Mamalis

Research output: Contribution to journalArticle

Abstract

A case of infectious endophthalmitis caused by the saprophyte Exophiala werneckii is reported. This has not been recognized as a pathogen for ocular infections previously. The infection followed uncomplicated cataract surgery involving phacoemulsification and IOL implant. Clinical presentation was that of an indolent endophthalmitis with relatively acute onset. Pars plana vitrectomy, fungal stains, and culture established the diagnosis. Initial management consisted of empirical intravitreal injection of vancomycin, ceftazidime, and amphotericin B. Treatment was supplemented with a 3-week course of systemic fluconazole and topical therapy with natamycin, atropine, ciprofloxacin, and diclofenac. The visual acuity returned to 20/20-2 with no recurrence of infection. The source of the infection could not be determined. Fungal endophthalmitis has to be considered as a rare, though important, complication following ophthalmic surgery. Specific fungal stains and cultures are helpful for establishing the diagnosis early in the course of disease. E werneckii should be considered in the differential diagnosis of fungal endophthalmitis.

Original languageEnglish (US)
Pages (from-to)417-422
Number of pages6
JournalOphthalmic Surgery and Lasers
Volume31
Issue number5
StatePublished - Jan 1 2000
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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    Huber, C. E., Laberge, T., Schwiesow, T., Carroll, K., Bernstein, P. S., & Mamalis, N. (2000). Exophiala werneckii endophthalmitis following cataract surgery in an immunocompetent individual. Ophthalmic Surgery and Lasers, 31(5), 417-422.