Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

Siân Jones, Ralph H Hruban, Mihoko Kamiyama, Michael Borges, Xiaosong Zhang, D. Williams Parsons, Jimmy Cheng Ho Lin, Emily Palmisano, Kieran Brune, Elizabeth Jaffee, Christine A. Iacobuzio-Donahue, Anirban Maitra, Giovanni Parmigiani, Scott E Kern, Victor E Velculescu, Kenneth W Kinzler, Bert Vogelstein, James Eshleman, Michael S Goggins, Alison Klein

Research output: Contribution to journalArticle

Original languageEnglish (US)
Pages (from-to)217
Number of pages1
Issue number5924
StatePublished - Apr 10 2009


Tumor Suppressor Proteins
identification method
Germ-Line Mutation
Terminator Codon
Sequence Deletion
Neoplasm Genes
Genetic Predisposition to Disease
Nuclear Proteins
Pancreatic Neoplasms
DNA Sequence Analysis
gene expression
Breast Neoplasms
Gene Expression

ASJC Scopus subject areas

  • General

Cite this

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. / Jones, Siân; Hruban, Ralph H; Kamiyama, Mihoko; Borges, Michael; Zhang, Xiaosong; Parsons, D. Williams; Lin, Jimmy Cheng Ho; Palmisano, Emily; Brune, Kieran; Jaffee, Elizabeth; Iacobuzio-Donahue, Christine A.; Maitra, Anirban; Parmigiani, Giovanni; Kern, Scott E; Velculescu, Victor E; Kinzler, Kenneth W; Vogelstein, Bert; Eshleman, James; Goggins, Michael S; Klein, Alison.

In: Science, Vol. 324, No. 5924, 10.04.2009, p. 217.

Research output: Contribution to journalArticle

Jones, S, Hruban, RH, Kamiyama, M, Borges, M, Zhang, X, Parsons, DW, Lin, JCH, Palmisano, E, Brune, K, Jaffee, E, Iacobuzio-Donahue, CA, Maitra, A, Parmigiani, G, Kern, SE, Velculescu, VE, Kinzler, KW, Vogelstein, B, Eshleman, J, Goggins, MS & Klein, A 2009, 'Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene', Science, vol. 324, no. 5924, pp. 217. https://doi.org/10.1126/science.1171202
Jones, Siân ; Hruban, Ralph H ; Kamiyama, Mihoko ; Borges, Michael ; Zhang, Xiaosong ; Parsons, D. Williams ; Lin, Jimmy Cheng Ho ; Palmisano, Emily ; Brune, Kieran ; Jaffee, Elizabeth ; Iacobuzio-Donahue, Christine A. ; Maitra, Anirban ; Parmigiani, Giovanni ; Kern, Scott E ; Velculescu, Victor E ; Kinzler, Kenneth W ; Vogelstein, Bert ; Eshleman, James ; Goggins, Michael S ; Klein, Alison. / Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. In: Science. 2009 ; Vol. 324, No. 5924. pp. 217.
title = "Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene",
author = "Si{\^a}n Jones and Hruban, {Ralph H} and Mihoko Kamiyama and Michael Borges and Xiaosong Zhang and Parsons, {D. Williams} and Lin, {Jimmy Cheng Ho} and Emily Palmisano and Kieran Brune and Elizabeth Jaffee and Iacobuzio-Donahue, {Christine A.} and Anirban Maitra and Giovanni Parmigiani and Kern, {Scott E} and Velculescu, {Victor E} and Kinzler, {Kenneth W} and Bert Vogelstein and James Eshleman and Goggins, {Michael S} and Alison Klein",
year = "2009",
month = "4",
day = "10",
doi = "10.1126/science.1171202",
language = "English (US)",
volume = "324",
pages = "217",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "5924",



T1 - Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

AU - Jones, Siân

AU - Hruban, Ralph H

AU - Kamiyama, Mihoko

AU - Borges, Michael

AU - Zhang, Xiaosong

AU - Parsons, D. Williams

AU - Lin, Jimmy Cheng Ho

AU - Palmisano, Emily

AU - Brune, Kieran

AU - Jaffee, Elizabeth

AU - Iacobuzio-Donahue, Christine A.

AU - Maitra, Anirban

AU - Parmigiani, Giovanni

AU - Kern, Scott E

AU - Velculescu, Victor E

AU - Kinzler, Kenneth W

AU - Vogelstein, Bert

AU - Eshleman, James

AU - Goggins, Michael S

AU - Klein, Alison

PY - 2009/4/10

Y1 - 2009/4/10

UR - http://www.scopus.com/inward/record.url?scp=64849092309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=64849092309&partnerID=8YFLogxK

U2 - 10.1126/science.1171202

DO - 10.1126/science.1171202

M3 - Article

VL - 324

SP - 217

JO - Science

JF - Science

SN - 0036-8075

IS - 5924

ER -