Exercise and the Endogenous Opioids

Steven R. Gambert; Thad C. Hagen; Thomas L. Garthwaite; Edmund H. Duthie; Daniel J. Mccarty; Lorin M. Hawley; Gail E. Butterfield; Peter A. Farrell; Daniel B. Carr; Beverly A. Bullen; Gary S. Skrinar; Michael A. Arnold; Michael Rosenblatt; Inese Z. Beitins; Joseph B. Martin; Janet W. Mcarthur

doi:10.1056/NEJM198112243052619

Exercise and the Endogenous Opioids

Steven R. Gambert, Thad C. Hagen, Thomas L. Garthwaite, Edmund H. Duthie, Daniel J. Mccarty, Lorin M. Hawley, Gail E. Butterfield, Peter A. Farrell, Daniel B. Carr, Beverly A. Bullen, Gary S. Skrinar, Michael A. Arnold, Michael Rosenblatt, Inese Z. Beitins, Joseph B. Martin, Janet W. Mcarthur

School of Medicine

Research output: Contribution to journal › Letter › peer-review

31 Scopus citations

Abstract

To the Editor: We read with great interest the paper by Carr et al. in the September 3 issue¹ on the relation between exercise and β-endorphin secretion in women. We have previously reported a study in which five untrained subjects (four men and one woman) 26 to 35 years old ran for 20 minutes on a treadmill at a speed that was adjusted to maintain the heart rate at 80 per cent of maximum.² Plasma samples were obtained before and after exercise, and β-endorphin immunoreactivity was measured by radioimmunoassay. There was a 440 per cent mean increase in circulating β-endorphin.

Original language	English (US)
Pages (from-to)	1590-1592
Number of pages	3
Journal	New England Journal of Medicine
Volume	305
Issue number	26
DOIs	https://doi.org/10.1056/NEJM198112243052619
State	Published - Dec 24 1981

ASJC Scopus subject areas

Medicine(all)

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10.1056/NEJM198112243052619

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Gambert, S. R., Hagen, T. C., Garthwaite, T. L., Duthie, E. H., Mccarty, D. J., Hawley, L. M., Butterfield, G. E., Farrell, P. A., Carr, D. B., Bullen, B. A., Skrinar, G. S., Arnold, M. A., Rosenblatt, M., Beitins, I. Z., Martin, J. B., & Mcarthur, J. W. (1981). Exercise and the Endogenous Opioids. New England Journal of Medicine, 305(26), 1590-1592. https://doi.org/10.1056/NEJM198112243052619

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title = "Exercise and the Endogenous Opioids",

abstract = "To the Editor: We read with great interest the paper by Carr et al. in the September 3 issue1 on the relation between exercise and β-endorphin secretion in women. We have previously reported a study in which five untrained subjects (four men and one woman) 26 to 35 years old ran for 20 minutes on a treadmill at a speed that was adjusted to maintain the heart rate at 80 per cent of maximum.2 Plasma samples were obtained before and after exercise, and β-endorphin immunoreactivity was measured by radioimmunoassay. There was a 440 per cent mean increase in circulating β-endorphin.",

author = "Gambert, {Steven R.} and Hagen, {Thad C.} and Garthwaite, {Thomas L.} and Duthie, {Edmund H.} and Mccarty, {Daniel J.} and Hawley, {Lorin M.} and Butterfield, {Gail E.} and Farrell, {Peter A.} and Carr, {Daniel B.} and Bullen, {Beverly A.} and Skrinar, {Gary S.} and Arnold, {Michael A.} and Michael Rosenblatt and Beitins, {Inese Z.} and Martin, {Joseph B.} and Mcarthur, {Janet W.}",

year = "1981",

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doi = "10.1056/NEJM198112243052619",

language = "English (US)",

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pages = "1590--1592",

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TY - JOUR

T1 - Exercise and the Endogenous Opioids

AU - Gambert, Steven R.

AU - Hagen, Thad C.

AU - Garthwaite, Thomas L.

AU - Duthie, Edmund H.

AU - Mccarty, Daniel J.

AU - Hawley, Lorin M.

AU - Butterfield, Gail E.

AU - Farrell, Peter A.

AU - Carr, Daniel B.

AU - Bullen, Beverly A.

AU - Skrinar, Gary S.

AU - Arnold, Michael A.

AU - Rosenblatt, Michael

AU - Beitins, Inese Z.

AU - Martin, Joseph B.

AU - Mcarthur, Janet W.

PY - 1981/12/24

Y1 - 1981/12/24

N2 - To the Editor: We read with great interest the paper by Carr et al. in the September 3 issue1 on the relation between exercise and β-endorphin secretion in women. We have previously reported a study in which five untrained subjects (four men and one woman) 26 to 35 years old ran for 20 minutes on a treadmill at a speed that was adjusted to maintain the heart rate at 80 per cent of maximum.2 Plasma samples were obtained before and after exercise, and β-endorphin immunoreactivity was measured by radioimmunoassay. There was a 440 per cent mean increase in circulating β-endorphin.

AB - To the Editor: We read with great interest the paper by Carr et al. in the September 3 issue1 on the relation between exercise and β-endorphin secretion in women. We have previously reported a study in which five untrained subjects (four men and one woman) 26 to 35 years old ran for 20 minutes on a treadmill at a speed that was adjusted to maintain the heart rate at 80 per cent of maximum.2 Plasma samples were obtained before and after exercise, and β-endorphin immunoreactivity was measured by radioimmunoassay. There was a 440 per cent mean increase in circulating β-endorphin.

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EP - 1592

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 26

ER -

Exercise and the Endogenous Opioids

Abstract

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