Excessive Weight Gain Associated with Dolutegravir Initiation in a 10-Year-Old Female with Perinatally Acquired Human Immunodeficiency Virus: A Case Report and Review of the Literature

J. Li, E. H. Yusuf, A. L. Agwu

Research output: Contribution to journalReview articlepeer-review

Abstract

Children with perinatally acquired human immunodeficiency virus (PHIV) face a lifetime of combination antiretroviral treatment that often includes dolutegravir (DTG). DTG, an integrase strand inhibitor that has been linked to weight gain in adults, is increasingly being used in children. Understanding its potential short- and long-term sequelae in children is critically important. We report a case of excessive weight gain in a child with PHIV on DTG and provide a brief literature review.

Original languageEnglish (US)
Pages (from-to)373-375
Number of pages3
JournalJournal of the Pediatric Infectious Diseases Society
Volume10
Issue number3
DOIs
StatePublished - Mar 1 2021

Keywords

  • dolutegravir
  • human immunodeficiency virus (HIV)
  • pediatric
  • perinatal
  • weight gain

ASJC Scopus subject areas

  • Medicine(all)

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