Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study

Eliseo Guallar, José R. Banegas, Elena Blasco-Colmenares, F. Javier Jiménez, Jean Dallongeville, Julian P. Halcox, Claudio Borghi, Elvira L. Massá-González, Mánica Tafalla, Joep Perk, Guy De Backer, Philippe G. Steg, Fernando Rodríguez-Artalejo

Research output: Contribution to journalArticle

Abstract

Background: Physicians involved in primary prevention are key players in CVD risk control strategies, but the expected reduction in CVD risk that would be obtained if all patients attending primary care had their risk factors controlled according to current guidelines is unknown. The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe. Methods. Cross-sectional study using data from the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA), which involved primary care and outpatient clinics involved in primary prevention from 12 European countries between May 2009 and January 2010. We enrolled 7,434 patients over 50 years old with at least one cardiovascular risk factor but without CVD and calculated their 10-year risk of CVD death according to the SCORE equation, modified to take diabetes risk into account. Results: The average 10-year risk of CVD death in study participants (N = 7,434) was 8.2%. Hypertension, hyperlipidemia, smoking, and diabetes were responsible for 32.7 (95% confidence interval 32.0-33.4), 15.1 (14.8-15.4), 10.4 (9.9-11.0), and 16.4% (15.6-17.2) of CVD risk, respectively. The four risk factors accounted for 57.7% (57.0-58.4) of CVD risk, representing a 10-year excess risk of CVD death of 5.66% (5.47-5.85). Lack of control of hypertension, hyperlipidemia, smoking, and diabetes were responsible for 8.8 (8.3-9.3), 10.6 (10.3-10.9), 10.4 (9.9-11.0), and 3.1% (2.8-3.4) of CVD risk, respectively. Lack of control of the four risk factors accounted for 29.2% (28.5-29.8) of CVD risk, representing a 10-year excess risk of CVD death of 3.12% (2.97-3.27). Conclusions: Lack of control of CVD risk factors was responsible for almost 30% of the risk of CVD death among patients participating in the EURIKA Study.

Original languageEnglish (US)
Article number704
JournalBMC Public Health
Volume11
DOIs
StatePublished - 2011

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Primary Prevention
Primary Health Care
Hyperlipidemias
Smoking
Hypertension
Risk Management
Ambulatory Care Facilities
Cross-Sectional Studies
Guidelines
Confidence Intervals
Physicians

Keywords

  • cardiovascular disease
  • control
  • mortality
  • risk factors
  • SCORE

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Guallar, E., Banegas, J. R., Blasco-Colmenares, E., Jiménez, F. J., Dallongeville, J., Halcox, J. P., ... Rodríguez-Artalejo, F. (2011). Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study. BMC Public Health, 11, [704]. https://doi.org/10.1186/1471-2458-11-704

Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study. / Guallar, Eliseo; Banegas, José R.; Blasco-Colmenares, Elena; Jiménez, F. Javier; Dallongeville, Jean; Halcox, Julian P.; Borghi, Claudio; Massá-González, Elvira L.; Tafalla, Mánica; Perk, Joep; De Backer, Guy; Steg, Philippe G.; Rodríguez-Artalejo, Fernando.

In: BMC Public Health, Vol. 11, 704, 2011.

Research output: Contribution to journalArticle

Guallar, E, Banegas, JR, Blasco-Colmenares, E, Jiménez, FJ, Dallongeville, J, Halcox, JP, Borghi, C, Massá-González, EL, Tafalla, M, Perk, J, De Backer, G, Steg, PG & Rodríguez-Artalejo, F 2011, 'Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study', BMC Public Health, vol. 11, 704. https://doi.org/10.1186/1471-2458-11-704
Guallar, Eliseo ; Banegas, José R. ; Blasco-Colmenares, Elena ; Jiménez, F. Javier ; Dallongeville, Jean ; Halcox, Julian P. ; Borghi, Claudio ; Massá-González, Elvira L. ; Tafalla, Mánica ; Perk, Joep ; De Backer, Guy ; Steg, Philippe G. ; Rodríguez-Artalejo, Fernando. / Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study. In: BMC Public Health. 2011 ; Vol. 11.
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abstract = "Background: Physicians involved in primary prevention are key players in CVD risk control strategies, but the expected reduction in CVD risk that would be obtained if all patients attending primary care had their risk factors controlled according to current guidelines is unknown. The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe. Methods. Cross-sectional study using data from the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA), which involved primary care and outpatient clinics involved in primary prevention from 12 European countries between May 2009 and January 2010. We enrolled 7,434 patients over 50 years old with at least one cardiovascular risk factor but without CVD and calculated their 10-year risk of CVD death according to the SCORE equation, modified to take diabetes risk into account. Results: The average 10-year risk of CVD death in study participants (N = 7,434) was 8.2{\%}. Hypertension, hyperlipidemia, smoking, and diabetes were responsible for 32.7 (95{\%} confidence interval 32.0-33.4), 15.1 (14.8-15.4), 10.4 (9.9-11.0), and 16.4{\%} (15.6-17.2) of CVD risk, respectively. The four risk factors accounted for 57.7{\%} (57.0-58.4) of CVD risk, representing a 10-year excess risk of CVD death of 5.66{\%} (5.47-5.85). Lack of control of hypertension, hyperlipidemia, smoking, and diabetes were responsible for 8.8 (8.3-9.3), 10.6 (10.3-10.9), 10.4 (9.9-11.0), and 3.1{\%} (2.8-3.4) of CVD risk, respectively. Lack of control of the four risk factors accounted for 29.2{\%} (28.5-29.8) of CVD risk, representing a 10-year excess risk of CVD death of 3.12{\%} (2.97-3.27). Conclusions: Lack of control of CVD risk factors was responsible for almost 30{\%} of the risk of CVD death among patients participating in the EURIKA Study.",
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AU - Guallar, Eliseo

AU - Banegas, José R.

AU - Blasco-Colmenares, Elena

AU - Jiménez, F. Javier

AU - Dallongeville, Jean

AU - Halcox, Julian P.

AU - Borghi, Claudio

AU - Massá-González, Elvira L.

AU - Tafalla, Mánica

AU - Perk, Joep

AU - De Backer, Guy

AU - Steg, Philippe G.

AU - Rodríguez-Artalejo, Fernando

PY - 2011

Y1 - 2011

N2 - Background: Physicians involved in primary prevention are key players in CVD risk control strategies, but the expected reduction in CVD risk that would be obtained if all patients attending primary care had their risk factors controlled according to current guidelines is unknown. The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe. Methods. Cross-sectional study using data from the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA), which involved primary care and outpatient clinics involved in primary prevention from 12 European countries between May 2009 and January 2010. We enrolled 7,434 patients over 50 years old with at least one cardiovascular risk factor but without CVD and calculated their 10-year risk of CVD death according to the SCORE equation, modified to take diabetes risk into account. Results: The average 10-year risk of CVD death in study participants (N = 7,434) was 8.2%. Hypertension, hyperlipidemia, smoking, and diabetes were responsible for 32.7 (95% confidence interval 32.0-33.4), 15.1 (14.8-15.4), 10.4 (9.9-11.0), and 16.4% (15.6-17.2) of CVD risk, respectively. The four risk factors accounted for 57.7% (57.0-58.4) of CVD risk, representing a 10-year excess risk of CVD death of 5.66% (5.47-5.85). Lack of control of hypertension, hyperlipidemia, smoking, and diabetes were responsible for 8.8 (8.3-9.3), 10.6 (10.3-10.9), 10.4 (9.9-11.0), and 3.1% (2.8-3.4) of CVD risk, respectively. Lack of control of the four risk factors accounted for 29.2% (28.5-29.8) of CVD risk, representing a 10-year excess risk of CVD death of 3.12% (2.97-3.27). Conclusions: Lack of control of CVD risk factors was responsible for almost 30% of the risk of CVD death among patients participating in the EURIKA Study.

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