Excellent results with calcineurin inhibitor-free initial immunosuppression in old recipients of old kidneys

C. Bösmüller, R. Öllinger, W. Mark, Gerald Brandacher, S. Schneeberger, F. Cakar, H. Bonatti, R. Margreiter

Research output: Contribution to journalArticle

Abstract

The ever increasing demand for donor organs has forced transplant surgeons to liberalize selection criteria. To avoid initial nephrotoxicity to kidneys from donors over 65 years of age, immunosuppression was begun with an IL-2 receptor antibody, mycophenolate mofetil, and steroids in a total of 38 recipients over 65 years. Calcineurin inhibitors (CI) were added after sufficient graft function was reached. After a mean cold ischemia time of 14:01 hours and a delayed function rate of 31%, patient survival, graft survival, and serum creatinine were 97.4%, 94.7%, and 1.5 mg/dL at 1 and 92.1%, 92.1%, and 1.7 mg/dL at 2 years, respectively. Thus, excellent results can be achieved in old recipients of old donor kidneys with CI-free initial immunosuppression.

Original languageEnglish (US)
Pages (from-to)881-883
Number of pages3
JournalTransplantation Proceedings
Volume37
Issue number2
DOIs
StatePublished - Mar 2005
Externally publishedYes

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Immunosuppression
Tissue Donors
Kidney
Mycophenolic Acid
Transplants
Cold Ischemia
Interleukin-2 Receptors
Graft Survival
Patient Selection
Creatinine
Steroids
Survival
Antibodies
Serum
Calcineurin Inhibitors
Surgeons

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Excellent results with calcineurin inhibitor-free initial immunosuppression in old recipients of old kidneys. / Bösmüller, C.; Öllinger, R.; Mark, W.; Brandacher, Gerald; Schneeberger, S.; Cakar, F.; Bonatti, H.; Margreiter, R.

In: Transplantation Proceedings, Vol. 37, No. 2, 03.2005, p. 881-883.

Research output: Contribution to journalArticle

Bösmüller, C, Öllinger, R, Mark, W, Brandacher, G, Schneeberger, S, Cakar, F, Bonatti, H & Margreiter, R 2005, 'Excellent results with calcineurin inhibitor-free initial immunosuppression in old recipients of old kidneys', Transplantation Proceedings, vol. 37, no. 2, pp. 881-883. https://doi.org/10.1016/j.transproceed.2004.12.028
Bösmüller, C. ; Öllinger, R. ; Mark, W. ; Brandacher, Gerald ; Schneeberger, S. ; Cakar, F. ; Bonatti, H. ; Margreiter, R. / Excellent results with calcineurin inhibitor-free initial immunosuppression in old recipients of old kidneys. In: Transplantation Proceedings. 2005 ; Vol. 37, No. 2. pp. 881-883.
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