Examination of Aggression and Self-injury in Children with Autism Spectrum Disorders and Serious Behavioral Problems

Devon Carroll, Victoria Hallett, Christopher J. McDougle, Michael G. Aman, James T. McCracken, Elaine Tierney, L. Eugene Arnold, Denis G. Sukhodolsky, Luc Lecavalier, Benjamin L. Handen, Naomi Swiezy, Cynthia Johnson, Karen Bearss, Benedetto Vitiello, Lawrence Scahill

Research output: Contribution to journalReview articlepeer-review

Abstract

This study identified subtypes of aggression in a sample of 206 children with autism spectrum disorder (ASD) who participated in 2 risperidone trials. The narratives were derived from a parent interview about each child's 2 most pressing problems. Five subtypes of aggression emerged: hot aggression only, cold aggression only, self-injurious behavior (SIB) only, aggression and SIB, and nonaggressive. All groups showed a high rate of positive response to risperidone with no differences across subtypes. These study findings extend understanding of aggression in ASD and may be useful to guide further study on biological mechanisms and individualized treatment in ASD.

Original languageEnglish (US)
Pages (from-to)57-72
Number of pages16
JournalChild and Adolescent Psychiatric Clinics of North America
Volume23
Issue number1
DOIs
StatePublished - Jan 2014

Keywords

  • Aggression
  • Autism
  • Disruptive behavior
  • Self-injury

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health

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